Quality Segment
assay
95%
form
powder or crystals
reaction suitability
reaction type: C-C Bond Formation
storage temp.
2-8°C
General description
1-((3,5-Difluorophenyl)sulfonyl)bicyclo[1.1.0]butane can be used as a cyclobutylation agent to introduce bicyclobutane group onto a variety of amines and thiols without affecting other functional groups.
Application
The following "spring-loaded" electrophile is a convenient reagent for the installation of cyclobutane to primary and secondary amines. This product is one of several synthetically useful reagents reported by Baran and coworkers on strain-release amination.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable