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B22852

Benzylhydrazine dihydrochloride

Name: Benzylhydrazine dihydrochloride
Brand: ALDRICH

97%

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About This Item

Linear Formula:

C₆H₅CH₂NHNH₂ · 2HCl

CAS Number:

20570-96-1

Molecular Weight:

195.09

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24891643

EC Number:

243-887-1

Beilstein/REAXYS Number:

3688990

MDL number:

MFCD00012921

Assay:

97%

Form:

powder

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Properties

Quality Level

200

assay

97%

form

powder

mp

143-145 °C (dec.) (lit.)

SMILES string

Cl.Cl.NNCc1ccccc1

InChI

1S/C7H10N2.2ClH/c8-9-6-7-4-2-1-3-5-7;;/h1-5,9H,6,8H2;2*1H

InChI key

MSJHOJKVMMEMNX-UHFFFAOYSA-N

Description

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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The inactivation of bifunctional peptidylglycine alpha-amidating enzyme by benzylhydrazine: evidence that the two enzyme-bound copper atoms are nonequivalent.

D J Merkler et al.

Archives of biochemistry and biophysics, 317(1), 93-102 (1995-02-20)

Peptidylglycine alpha-amidating enzyme catalyzes the two-step conversion of C-terminal glycine-extended peptides to C-terminal alpha-amidated peptides and glyoxylate in a reaction that requires O2, ascorbate and 2 mol of copper per mole of enzyme [Kulathila et al. (1994) Arch. Biochem. Biophys.

Benzylhydrazine as a pseudo-substrate of bovine serum amine oxidase.

L Morpurgo et al.

The Biochemical journal, 260(1), 19-25 (1989-05-15)

Bovine serum amine oxidase is inhibited by benzylhydrazine (BHy), but recovers full activity after a few hours incubation [Hucko-Haas & Reed (1970) Biochem. Biophys. Res. Commun. 38, 396-400]. The first phase of the process, requiring about 15 min, was found

Discovery and SAR of indole-2-carboxylic acid benzylidene-hydrazides as a new series of potent apoptosis inducers using a cell-based HTS assay.

Han-Zhong Zhang et al.

Bioorganic & medicinal chemistry, 12(13), 3649-3655 (2004-06-10)

A series of indole-2-carboxylic acid benzylidene-hydrazides has been identified as a new class of potent apoptosis inducers through a novel cell-based caspase HTS assay. The screening hit, 5-chloro-3-methyl-indole-2-carboxylic acid (4-nitrobenzylidene)-hydrazide (3a), was found to arrest T47D cells in G(2)/M and

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Global Trade Item Number

SKU	GTIN
B22852-100G	04061832763781
B22852-25G	04061832763798
B22852-5G	04061833426715