B2761
5-Bromoindole-2-carboxylic acid
98%
Synonym(s):
NSC 73384
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About This Item
Linear Formula:
C9H6NO2Br
CAS Number:
Molecular Weight:
240.05
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
98%
Form:
powder
InChI
1S/C9H6BrNO2/c10-6-1-2-7-5(3-6)4-8(11-7)9(12)13/h1-4,11H,(H,12,13)
SMILES string
OC(=O)c1cc2cc(Br)ccc2[nH]1
InChI key
YAULOOYNCJDPPU-UHFFFAOYSA-N
assay
98%
form
powder
storage temp.
−20°C
Quality Level
Application
Reactant involved in studies of biologically active molecules including:
- Discovery of indole inhibitors of MMP-13 for treatment of arthritic diseases
- Synthesis of indolyl ethanones as indoleamine 2,3-dioxygenase inhibitors
- cis-Diaminocyclohexane derivatives prepared for use as factor Xa inhibitors
- Synthesis of tubulin polymerization inhibitors and cancer cell growth inhibitors
- Preparation of dual PPARγ/δ agonists
- Synthesis of chemical probes to examine the role of hFPRL1 receptor in inflammation
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Shahrbanoo Jahangir et al.
Stem cell research & therapy, 11(1), 436-436 (2020-10-11)
Mesenchymal stem cells are a promising cell source for chondrogenic differentiation and have been widely used in several preclinical and clinical studies. However, they are prone to an unwanted differentiation process towards hypertrophy that limits their therapeutic efficacy. Matrix metallopeptidase
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