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About This Item
Linear Formula:
(CH3OCH2CH2)2NH
CAS Number:
Molecular Weight:
133.19
Beilstein:
1736313
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Assay
98%
form
liquid
refractive index
n20/D 1.419 (lit.)
bp
170-172 °C (lit.)
density
0.902 g/mL at 25 °C (lit.)
SMILES string
COCCNCCOC
InChI
1S/C6H15NO2/c1-8-5-3-7-4-6-9-2/h7H,3-6H2,1-2H3
InChI key
IBZKBSXREAQDTO-UHFFFAOYSA-N
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Application
Bis(2-methoxyethyl)amine can be used as a reactant:
- In the Pd-catalyzed Buchwald-Hartwig amination reaction to synthesize aryl amines by reacting with aryl and heteroaryl halides.
- To synthesize α-ketoamides via metal-free oxidative coupling reaction with methyl ketones in the presence of tert-butyl hydroperoxide as an oxidant and iodine as a catalyst.
- To synthesize N, N-dialkyl perfluoroalkanesulfonamides by reacting with perfluoroalkanesulfonyl halides.
- To synthesize N-(alkoxy)succinamide ester by reacting with succinyl chloride, which can be used as an intermediate to prepare diol monomer for biodegradable polyester synthesis.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B
Storage Class Code
3 - Flammable liquids
WGK
WGK 3
Flash Point(F)
136.4 °F - closed cup
Flash Point(C)
58 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
危险化学品
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Guo Fan Jin et al.
Molecules (Basel, Switzerland), 23(9) (2018-09-12)
Morpholine- and bis(2-methoxyethyl)amine-substituted 1,3,5-triazine derivatives containing an alkoxy-o-carborane in the 6-position of the triazine ring were successfully synthesized. The molecular structures of the methoxy- and ethoxy-o-carboranyl-1,3,5-triazines were established by X-ray crystallography. In vitro studies showed that the methylene bridged morpholine-
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