B5453
2-Benzimidazolylurea
98%
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About This Item
Empirical Formula (Hill Notation):
C8H8N4O
CAS Number:
Molecular Weight:
176.18
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
246-209-2
MDL number:
Assay:
98%
Form:
powder
InChI
1S/C8H8N4O/c9-7(13)12-8-10-5-3-1-2-4-6(5)11-8/h1-4H,(H4,9,10,11,12,13)
InChI key
LNYZEFQMIURYEI-UHFFFAOYSA-N
SMILES string
NC(=O)Nc1nc2ccccc2[nH]1
assay
98%
form
powder
mp
>300 °C (lit.)
Quality Level
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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R S Gupta
Biochemical and biophysical research communications, 143(1), 225-232 (1987-02-27)
The cross resistance patterns of a set of nocodazole-resistant (NocR) and podophyllotoxin-resistant (PodR) mutants of Chinese hamster ovary cells, which exhibit highly specific cross resistance towards compounds that show nocodazole-like antimitotic activity, towards a large number of benzimidazole derivatives have
S Trivulzio
Pharmacological research communications, 20(12), 1035-1046 (1988-12-01)
2-Benzimidazolylurea (BIU) decreases gastric acid secretion. The antisecretive activity appears to be associated with antihistaminic and antimuscarinic effects. The antihistaminic activity of BIU appears from its inhibitory effects on betazole stimulated gastric acid secretion and from its inhibitory activity on
Liang Hong et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(27), 9971-9976 (2014-06-10)
The voltage-gated proton channel Hv1 plays important roles in proton extrusion, pH homeostasis, and production of reactive oxygen species in a variety of cell types. Excessive Hv1 activity increases proliferation and invasiveness in cancer cells and worsens brain damage in
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