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About This Item
Empirical Formula (Hill Notation):
C15H14ClN3O4S3
CAS Number:
Molecular Weight:
431.94
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
202-061-0
MDL number:
Form:
solid
InChI key
NDTSRXAMMQDVSW-UHFFFAOYSA-N
InChI
1S/C15H14ClN3O4S3/c16-11-6-12-14(7-13(11)25(17,20)21)26(22,23)19-15(18-12)9-24-8-10-4-2-1-3-5-10/h1-7H,8-9H2,(H,18,19)(H2,17,20,21)
SMILES string
NS(=O)(=O)c1cc2c(NC(CSCc3ccccc3)=NS2(=O)=O)cc1Cl
form
solid
Quality Level
Gene Information
human ... SLC12A3(6559)
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Related Categories
signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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L R Berkowitz
The American journal of physiology, 258(4 Pt 1), C622-C629 (1990-04-01)
The thioalkylating agent N-ethylmaleimide (NEM) causes ouabain-insensitive K loss from human red blood cells. This K loss is inhibited when intracellular Cl is replaced by another permeant anion or when loop diuretics are placed in the incubation medium after NEM
Thiazides XIII: Dissolution testing: a bioavailability predictor for benzthiazide tablets.
V P Shah et al.
Biopharmaceutics & drug disposition, 3(3), 283-285 (1982-07-01)
R A Adler et al.
Metabolism: clinical and experimental, 35(7), 668-672 (1986-07-01)
There is evidence that prolactin (PRL) excess plays a role in the etiology of osteoporosis associated with human prolactinoma. Calcium balance in human hyperprolactinemia has not been thoroughly investigated. In the present study, rats with excess circulating PRL levels (male
M C Meyer et al.
Biopharmaceutics & drug disposition, 3(1), 1-9 (1982-01-01)
An assay was developed for benzthiazide in plasma, urine and feces, using high performance liquid chromatography (HPLC). A reverse-phase column was employed, with quantitation af 280 nm, using polythiazide as an internal standard. In three of four human subjects who
S K Wiedme et al.
Journal of capillary electrophoresis and microchip technology, 6(5-6), 163-168 (2001-10-30)
Interactions between diuretics and a recently synthesized temperature-responsive neutral copolymer, poly(N-isopropyl acrylamide) (PNIPA) grafted with poly(ethyleneoxide) (PEO) (PNIPA-g-PEO) were investigated by capillary electrophoresis and dynamic light scattering (DLS). At ambient temperatures, the copolymer takes an open, random coil conformation, but
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