B79803
3-Bromopropylamine hydrobromide
98%
Synonym(s):
3-Aminopropyl bromide hydrobromide
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About This Item
Linear Formula:
BrCH2CH2CH2NH2 · HBr
CAS Number:
Molecular Weight:
218.92
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
225-675-0
Beilstein/REAXYS Number:
3906418
MDL number:
Assay:
98%
Form:
crystals
InChI key
PQIYSSSTRHVOBW-UHFFFAOYSA-N
InChI
1S/C3H8BrN.BrH/c4-2-1-3-5;/h1-3,5H2;1H
SMILES string
Br.NCCCBr
assay
98%
form
crystals
mp
171-172 °C (lit.)
Quality Level
Related Categories
Application
3-Bromopropylamine hydrobromide is commonly used as a reagent to introduce propylamine group to the molecular skeleton. Some of the other reported applications include:
- Synthesis of photochemically and thermally reactive azobenzene rotaxane and indolocarbazole-containing [2]rotaxane.
- Synthesis of indenoisoquinoline based active topoisomerase I inhibitors as anticancer agents.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Maya Juenet et al.
Biomaterials, 156, 204-216 (2017-12-08)
Injection of recombinant tissue plasminogen activator (rt-PA) is the standard drug treatment for thrombolysis. However, rt-PA shows risk of hemorrhages and limited efficiency even at high doses. Polysaccharide-poly(isobutylcyanoacrylate) nanoparticles functionalized with fucoidan and loaded with rt-PA were designed to accumulate
Interlocked host anion recognition by an indolocarbazole-containing [2] rotaxane.
Brown A, et al.
Journal of the American Chemical Society, 131(13), 4937-4952 (2009)
Synthesis and anticancer activity of simplified indenoisoquinoline topoisomerase I inhibitors lacking substituents on the aromatic rings.
Nagarajan M, et al.
Journal of Medicinal Chemistry, 47(23), 5651-5661 (2004)
Christina Gladkova et al.
Nature, 559(7714), 410-414 (2018-07-12)
Mutations in the E3 ubiquitin ligase parkin (PARK2, also known as PRKN) and the protein kinase PINK1 (also known as PARK6) are linked to autosomal-recessive juvenile parkinsonism (AR-JP)1,2; at the cellular level, these mutations cause defects in mitophagy, the process
A multi-mode-driven molecular shuttle: photochemically and thermally reactive azobenzene rotaxanes.
Murakami H, et al.
Journal of the American Chemical Society, 127(45), 15891-15899 (2005)
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