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C102202

Sigma-Aldrich

Cyclohexanone oxime

97%

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Linear Formula:
C6H10(=NOH)
CAS Number:
Molecular Weight:
113.16
Beilstein:
1616769
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

97%

form

crystals

bp

206-210 °C (lit.)

mp

86-89 °C (lit.)

SMILES string

O\N=C1/CCCCC1

InChI

1S/C6H11NO/c8-7-6-4-2-1-3-5-6/h8H,1-5H2

InChI key

VEZUQRBDRNJBJY-UHFFFAOYSA-N

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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R E Glover et al.
Chemical research in toxicology, 12(10), 952-957 (1999-10-20)
Cyclohexanone oxime (CHOX), an intermediate used in the synthesis of polycaprolactam (Nylon-6), has been reported to be hematotoxic in Fischer rats. The in vivo metabolism of CHOX was found to release nitric oxide, which was detected in venous blood by
S C Gad et al.
Fundamental and applied toxicology : official journal of the Society of Toxicology, 5(1), 128-136 (1985-02-01)
Dermal exposure of rabbits to cyclohexanone oxime (CHO) for 24 hr at 0, 0.8, 2, and 5 g/kg caused dose-related reticulocytosis on the day after dosing as well as a decrease in hemoglobin in the 5-g/kg females 7 days postdosing.
Shelli J Schomaker et al.
Toxicology and applied pharmacology, 185(1), 48-54 (2002-12-04)
The purpose of these studies was to evaluate bone marrow from male CD rats following exposure to known hematotoxins using flow cytometry (FC) and a monoclonal antibody to the cell surface antigen CD71. Rats were treated with either CHO (300
Wen-Cui Li et al.
Journal of the American Chemical Society, 127(36), 12595-12600 (2005-09-08)
In this study, we present a synthetic pathway for the fabrication of self-supporting zeolite monoliths consisting of crystallized nanoparticles. A resorcinol-formaldehyde-based organic aerogel is used as a template, and silicalite-1 is used as the zeolite example. The silicalite-1 monoliths obtained
Raphaël Turgis et al.
ChemSusChem, 3(12), 1403-1408 (2010-12-01)
Brønsted-acidic ionic liquids that bear a sulfonic acid group, known as Forbes acids, show a good catalytic activity for the Beckmann rearrangement, used to prepare ε-caprolactam, which is a precursor of Nylon 6. The activity essentially stems from the acidity of

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