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Merck
CN

C11006

Carbohydrazide

98%

Synonym(s):

1,3-Diaminourea, Carbodihydrazide, Carbonohydrazide, N,N′-Diaminourea

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About This Item

Linear Formula:
CO(NHNH2)2
CAS Number:
Molecular Weight:
90.08
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
207-837-2
Beilstein/REAXYS Number:
1747069
MDL number:
Assay:
98%
Form:
crystals
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Quality Level

assay

98%

form

crystals

mp

150-153 °C (lit.)

SMILES string

NNC(=O)NN

InChI

1S/CH6N4O/c2-4-1(6)5-3/h2-3H2,(H2,4,5,6)

InChI key

XEVRDFDBXJMZFG-UHFFFAOYSA-N

Application

Carbohydrazide can be used:
  • As an oxygen scavenger.
  • In the synthesis of polydentate Schiff base ligands with various aldehydes and ligands by condensation.
  • In the synthesis of trifluoromethyl-containing (E)-N′-arylidene-1H-pyrazole-1-carbohydrazides by cyclocondensation reaction which shows antioxidant and antimicrobial properties.



pictograms

Exclamation markEnvironment

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Irrit. 2 - Skin Sens. 1

supp_hazards

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



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Marta Kisiel et al.
Journal of controlled release : official journal of the Controlled Release Society, 162(3), 646-653 (2012-08-21)
Understanding the influence of formulation and storage conditions on rhBMP-2 bioactivity is extremely important for its clinical application. Reports in the literature show that different research groups employ different parameters such as formulation conditions, storage, doses for in vivo applications
Ameen Ali Abu-Hashem et al.
Acta pharmaceutica (Zagreb, Croatia), 60(3), 311-323 (2010-12-08)
2-Amino-5-acetyl-4-methyl-thiophene-3-carboxylic acid ethyl ester (1) and 5-acetyl-2-amino-4-methylthiophene-3-carbohydrazide (2) were synthesized and used as starting materials for the synthesis of new series of 1-(5-amino-4-(3,5-dimethyl-1H-pyrazole-1-carbonyl)-3-methylthiophen-2-yl) ethanone (3a), 1-(5-amino-4-(4-chloro-3,5-dimethyl-1H-pyrazole-1-carbonyl)-3-methylthiophen-2-yl) ethanone (3b), 1-(4-methyl-2-amino-5-acetylthiophene-3-carbonyl)pyrazolidine-3,5-dione (4), (Z)-N'-(4-methyl-2-amino-5-acetylthiophene-3-carbonyl) formohydrazonic acid (5a), (Z)-ethyl-N'-4-methyl-2-amino-5-acetylthiophene-3-carbonylformo hydrazonate (5b), 6-acetyl-3-amino-2,5-dimethylthieno[2,3-d]pyrimidin-4(3H)-one (8), 5-methyl-3-amino-2-mercapto-6-acetylthieno
Alessandro K Jordão et al.
Bioorganic & medicinal chemistry, 19(18), 5605-5611 (2011-08-16)
Tuberculosis treatment remains a challenge that requires new antitubercular agents due to the emergence of multidrug-resistant Mycobacterium strains. This paper describes the synthesis, the antitubercular activity and the theoretical analysis of N-substituted-phenylamino-5-methyl-1H-1,2,3-triazole-4-carbohydrazides (8a-b, 8e-f, 8i-j and 8n-o) and new analogues



Global Trade Item Number

SKUGTIN
C11006-100G04061832493077
C11006-25G04061833460719