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Merck
CN

C121509

Cystamine dihydrochloride

96%

Synonym(s):

2,2′-Diaminodiethyl disulfide dihydrochloride, 2,2′-Dithiobis(ethylamine) dihydrochloride, Decarboxycystine dihydrochloride

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About This Item

Linear Formula:
NH2CH2CH2SSCH2CH2NH2 · 2HCl
CAS Number:
56-17-7
Molecular Weight:
225.20
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24892384
EC Number:
200-260-7
Beilstein/REAXYS Number:
3616850
MDL number:
MFCD00012905
Assay:
96%
Form:
powder

Key Documents

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InChI

1S/C4H12N2S2.2ClH/c5-1-3-7-8-4-2-6;;/h1-6H2;2*1H

InChI key

YUFRRMZSSPQMOS-UHFFFAOYSA-N

SMILES string

Cl[H].Cl[H].NCCSSCCN

assay

96%

form

powder

mp

217-220 °C (dec.) (lit.)

Quality Level

200

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Application

Cystamine dihydrochloride can be utilized as a building block in the synthesis of disulfide cross-linked oligodeoxyribonucleotides and psammaplin A . It can be also used to functionalize PGMA (poly(glycidyl methacrylate) microsphere) by introducing sulfhydryl groups for the further fabrication of silver nanoparticles (AgNPs).
Heparin antagonist and sulfhydryl modifying reagent

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM2188
BCCG6686
BCCC0034
BCBW5169
BCBQ0039V

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Synthesis and characterization of disulfide cross-linked oligonucleotides
Ferentz A E, et al.
Journal of the American Chemical Society, 115(20), 9006-9014 (1993)
In situ synthesis of monodisperse silver nanoparticles on sulfhydryl-functionalized poly (glycidyl methacrylate) microspheres for catalytic reduction of 4-nitrophenol
Zhang W, et al.
Industrial & Engineering Chemistry Research, 54(25), 6480-6488 (2015)
Qianjiao Yang et al.
Molecules (Basel, Switzerland), 15(12), 8784-8795 (2010-12-04)
Psammaplin F, an unsymmetrical disulfide bromotyrosine, was isolated from the sponge Pseudoceratina purpurea in 2003. We reported here the first total synthesis of psammaplin F in 12% overall yield by employing Cleland's reagent reduction as key step. The longest linear
Nan-Fu Chiu et al.
Nanoscale research letters, 13(1), 152-152 (2018-05-17)
In this study, we propose a modified gold nanoparticle-graphene oxide sheet (AuNP-GO) nanocomposite to detect two different interactions between proteins and hybrid nanocomposites for use in biomedical applications. GO sheets have high bioaffinity, which facilitates the attachment of biomolecules to
Shosuke Ito et al.
Biochemical pharmacology, 84(5), 646-653 (2012-06-26)
Metastatic melanoma is resistant to conventional therapies. N-propionyl-4-S-cysteaminylphenol (NPrCAP), an N-protected sulfur-amine analog of tyrosine, is a good substrate for tyrosinase and is selectively incorporated into melanoma cells, causing cytotoxicity in vitro and in vivo. We have recently shown that
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