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C47000

Sigma-Aldrich

5-Chloro-8-quinolinol

95%

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Synonym(s):
5-Chloro-8-hydroxyquinoline
Empirical Formula (Hill Notation):
C9H6ClNO
CAS Number:
130-16-5
Molecular Weight:
179.60
Beilstein:
5289
EC Number:
204-978-1
MDL number:
MFCD00006788
PubChem Substance ID:
24892714
NACRES:
NA.22

Assay

95%

form

crystals

mp

122-124 °C (lit.)

SMILES string

Oc1ccc(Cl)c2cccnc12

InChI

1S/C9H6ClNO/c10-7-3-4-8(12)9-6(7)2-1-5-11-9/h1-5,12H

InChI key

CTQMJYWDVABFRZ-UHFFFAOYSA-N

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Related Categories

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H315 - H319 - H335 - H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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V Arjunan et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 72(4), 783-788 (2008-12-30)
The Fourier transform infrared (FTIR) and FT-Raman spectra of 7-bromo-5-chloro-8-hydroxyquinoline (BCHQ) have been measured in the range 4000-400 and 4000-100cm(-1), respectively. Complete vibrational assignment and analysis of the fundamental modes of the compound were carried out using the observed FTIR
E J Wojtowicz
Journal of pharmaceutical sciences, 73(10), 1430-1433 (1984-10-01)
A reverse-phase high-performance liquid chromatographic (HPLC) method was developed for determining iodochlorhydroxyquin, 5,7-dichloro-8-hydroxyquinoline, and 5,7-diiodo-8-hydroxyquinoline in creams, ointments, shampoos, tablets, and bulk drugs. A column packed with 10-micron phenyl-silica and a mobile phase of 0.001 M NiCl2 in acetonitrile-methanol-water (30:20:50)
Poonpilas Hongmanee et al.
Antimicrobial agents and chemotherapy, 51(3), 1105-1106 (2006-12-21)
The in vitro activities of cloxyquin (5-chloroquinolin-8-ol) against 9 standard strains and 150 clinical isolates of Mycobacterium tuberculosis were studied. The MICs ranged from 0.062 to 0.25 microg/ml. The MIC(50) and MIC(90) were 0.125 and 0.25 microg/ml, respectively. These indicate
Oleg V Larionov et al.
Organic letters, 16(3), 864-867 (2014-01-15)
A one-step transformation of heterocyclic N-oxides to 2-alkyl-, aryl-, and alkenyl-substituted N-heterocycles is described. The success of this broad-scope methodology hinges on the combination of copper catalysis and activation by lithium fluoride or magnesium chloride. The utility of this method
Nikoleta Stoyanova et al.
Materials science & engineering. C, Materials for biological applications, 41, 119-126 (2014-06-09)
For the first time the preparation of defect-free fibers from immiscible blends of high molar mass poly(lactic acid) (PLA) and poly(butylene succinate) (PBS) in the whole range of the polyester weight ratios is shown. Electrospinning using the solvent-nonsolvent approach proved
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