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Merck
CN

D102008

1,3-Difluorobenzene

≥99%

Synonym(s):

1,3-Bisfluorobenzene, 1,3-Difluorobenzene, 2,4-Difluorobenzene, m-Difluorobenzene

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About This Item

Empirical Formula (Hill Notation):
C6H4F2
CAS Number:
Molecular Weight:
114.09
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
206-746-5
Beilstein/REAXYS Number:
1904537
MDL number:
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Product Name

1,3-Difluorobenzene, ≥99%

InChI key

UEMGWPRHOOEKTA-UHFFFAOYSA-N

InChI

1S/C6H4F2/c7-5-2-1-3-6(8)4-5/h1-4H

SMILES string

Fc1cccc(F)c1

assay

≥99%

form

liquid

refractive index

n20/D 1.438 (lit.)

bp

82 °C (lit.)

density

1.163 g/mL at 25 °C (lit.)

Quality Level

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pictograms

Flame

signalword

Danger

hcodes

pcodes

Hazard Classifications

Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

35.6 °F

flash_point_c

2 °C

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

危险化学品
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D Gala et al.
Journal of pharmaceutical sciences, 81(12), 1199-1203 (1992-12-01)
Alpha-Hydroxyaryl ketones such as 2-hydroxypropiophenone and 1-(2,4-difluorophenyl)-2-hydroxy-1-propanone, the key intermediates in the preparation of antifungal agents, decompose into oxidized, rearranged, and condensed products. These products were isolated and characterized. The possible mechanisms for the formation of the products are discussed.
Aujin Kim et al.
The Journal of organic chemistry, 71(5), 2170-2172 (2006-02-25)
A short, high-yielding synthesis of differentially substituted resorcinol derivatives has been developed that utilizes 1,3-difluorobenzene as the starting material and employs sequential nucleophilic aromatic substitution (S(N)Ar) reactions to generate desymmetrized products. The scope and limitations of the second S(N)Ar reaction

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