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Merck
CN

D161802

N,N′-Dimethylhydrazine dihydrochloride

98%

Synonym(s):

1,2-Dimethylhydrazine dihydrochloride, N,N′-Dimethylhydrazine (sym.) dihydrochloride

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About This Item

Linear Formula:
CH3NHNHCH3 · 2HCl
CAS Number:
Molecular Weight:
133.02
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
206-183-5
Beilstein/REAXYS Number:
3905684
MDL number:
Assay:
98%
Form:
crystals
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Quality Level

assay

98%

form

crystals

mp

167-169 °C (dec.) (lit.)

SMILES string

Cl[H].Cl[H].CNNC

InChI

1S/C2H8N2.2ClH/c1-3-4-2;;/h3-4H,1-2H3;2*1H

InChI key

WLDRFJDGKMTPPV-UHFFFAOYSA-N

Biochem/physiol Actions

Induces colon cancer in rats and mice.


signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Carc. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges



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Articles

Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.


Reema Narayan et al.
Carbohydrate polymers, 261, 117893-117893 (2021-03-27)
Glycosylated pH-sensitive mesoporous silica nanoparticles (MSNs) of capecitabine (CAP) were developed for targeting colorectal cancer. The MSNs possessed an average pore diameter of 8.12 ± 0.43 nm, pore volume of 0.73 ± 0.21 cm3/g, and particle size of 245.24 ±
Preety Ghanghas et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 78, 239-247 (2016-02-24)
Non-steroidal anti-inflammatory drugs (NSAIDs) are emerging as novel chemopreventive agents against a variety of cancers owing to their capability in blocking the tumor development by cellular proliferation and by promoting apoptosis. Inflammation is principal cause of colon carcinogenesis. A missing
Vijay L Kumar et al.
Drug development research, 80(8), 1089-1097 (2019-09-01)
Anti-inflammatory drugs are well known to reduce the risk of colon cancer and prophylactic use of such agents is gaining acceptance as a cancer prevention therapy. As artesunate, an antimalarial drug, has been shown to exhibit chemopreventive properties, the present



Global Trade Item Number

SKUGTIN
D161802-10G04061833560303
D161802-1G04061825772943