D186252
N,N-Dimethylsulfamoyl chloride
99%
Synonym(s):
Dimethylamidosulfonyl chloride, Dimethylaminosulfonyl chloride, Dimethylsulphamoyl chloride, N,N-Dimethylamidosulfonyl chloride, N,N-Dimethylaminosulfonyl chloride, N,N-Dimethylsulfamoyl chloride, N,N-Dimethylsulfamyl chloride
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About This Item
Quality Segment
assay
99%
form
liquid
refractive index
n
bp
114 °C/75 mmHg (lit.)
density
1.337 g/mL at 25 °C (lit.)
functional group
amine
SMILES string
CN(C)S(Cl)(=O)=O
InChI
1S/C2H6ClNO2S/c1-4(2)7(3,5)6/h1-2H3
InChI key
JFCHSQDLLFJHOA-UHFFFAOYSA-N
Application
- It is widely used in the synthesis of a medicinally important class of compounds, sulfonamides.
- It is used in the synthesis of aminotetralin derived sulfamides as anticancer agents and acetylcholinesterase inhibitors.
- It can also be used in the esterification/amidation between carboxylic acids and equimolar amounts of alcohols/amines, as in the synthesis of coumaperine.
signalword
Danger
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Carc. 1B - Eye Dam. 1 - Skin Corr. 1B
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
149.0 °F - closed cup
flash_point_c
65 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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