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Merck
CN

D7631

5,5-Dimethyl-2,4-oxazolidinedione

Synonym(s):

DMO, Dimethadione, NSC 30152

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About This Item

Empirical Formula (Hill Notation):
C5H7NO3
CAS Number:
Molecular Weight:
129.11
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
211-781-4
MDL number:
Form:
powder
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InChI key

JYJFNDQBESEHJQ-UHFFFAOYSA-N

InChI

1S/C5H7NO3/c1-5(2)3(7)6-4(8)9-5/h1-2H3,(H,6,7,8)

SMILES string

CC1(C)OC(=O)NC1=O

form

powder

mp

77-80 °C (lit.)

storage temp.

2-8°C

Quality Level

Application

Reactant involved in:
  • Synthesis of nickel benzoannulated or naphthoannulated β-oxatetraazachlorin complex
  • Being used as a cathepsin K inhibitor

Molecule involved in pharmacological studies including:
  • Identification of bioequivalent generic substitute for antiepileptic drugs
  • Screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis
  • Dissolving protein plugs in patients with choledochal cyst / pancreaticobiliary maljunctions

pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Shin Yoshitake et al.
Diabetologia, 62(3), 504-516 (2018-11-30)
In diabetic macular oedema (DMO), blood components passing through the disrupted blood-retinal barrier cause neuroinflammation, but the mechanism by which autoantibodies induce neuroglial dysfunction is unknown. The aim of this study was to identify a novel autoantibody and to evaluate
Thomas Lines et al.
Journal of phycology, 54(5), 599-607 (2018-07-29)
CO2 levels in freshwater systems can fluctuate widely, potentially influencing photosynthetic rates and growth of phytoplankton. Given the right conditions, this can lead to bloom formation and affect water quality. This study investigated the acquisition of dissolved inorganic carbon (DIC)
S E Andersson et al.
The Journal of rheumatology, 26(9), 2018-2024 (1999-09-24)
To measure intracellular and tissue pH in periarticular soft tissue during different phases of antigen induced arthritis in the rat. pH was calculated using the following values: (1) the distribution of [14C]-dimethyl-oxazolidinedione; (2) the total tissue water and the extracellular
Hemal Mehta et al.
The British journal of ophthalmology, 102(4), 479-482 (2017-08-06)
To determine whether early vision gains predict long-term visual outcomes in the BEVORDEX randomised clinical trial of bevacizumab or dexamethasone implants for diabetic macular oedema. Post hoc analysis of 68 study eyes (77%) that completed 2 years follow-up of the
D P Nolan et al.
European journal of biochemistry, 267(1), 18-27 (1999-12-22)
Natural infections of mammals with African trypanosomes, such as Trypanosoma brucei, are generally pleomorphic, the population consisting of different forms, termed slender and stumpy forms, that vary in number as the parasitaemia develops. We show that the differentiation of slender

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