D8402
1,2-Diacetylhydrazine
98%
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About This Item
Linear Formula:
CH3CONHNHCOCH3
CAS Number:
Molecular Weight:
116.12
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
221-576-1
MDL number:
Assay:
98%
Form:
powder
InChI
1S/C4H8N2O2/c1-3(7)5-6-4(2)8/h1-2H3,(H,5,7)(H,6,8)
InChI key
ZLHNYIHIHQEHJQ-UHFFFAOYSA-N
SMILES string
CC(=O)NNC(C)=O
assay
98%
form
powder
bp
209 °C/15 mmHg (lit.)
mp
138-140 °C (lit.)
Quality Level
Related Categories
signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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E B Bhalerao et al.
Indian journal of physiology and pharmacology, 29(2), 83-88 (1985-04-01)
Patients suffering from pulmonary tuberculosis were investigated for the levels of isoniazid (INH) and its metabolites viz. acetyl-INH, mono and diacetyl hydrazines and ammonia. It was observed that 50% of the patients are slow inactivators of INH and almost all
Qiqi Zhao et al.
Journal of agricultural and food chemistry, 56(13), 5254-5259 (2008-06-11)
A series of novel N-substituted phenoxysulfenyl- N'- tert-butyl- N, N'-diacylhydrazines were designed and synthesized as insect growth regulators via the key intermediates N-chlorosulfenyl- N'- tert-butyl- N, N'-diacylhydrazines. Compared to the parent compounds, these N-substituted phenoxysulfenyl derivatives displayed better solubility and
Ramachandran Azhakar et al.
Dalton transactions (Cambridge, England : 2003), 41(5), 1529-1533 (2011-12-14)
The reaction of N-heterocyclic silylene (NHSi) L [L = CH{(C[double bond, length as m-dash]CH(2))(CMe)(2,6-iPr(2)C(6)H(3)N)(2)}Si] with benzoylhydrazine, 1,2-dicarbethoxyhydrazine, 1,2-diacetylhydrazine and 1,2-bis(tert-butoxycarbonyl)hydrazine in 1 : 1 molar ratio resulted in compounds 1-4 with an almost quantitative yield and five coordinate silicon atoms.
W von Sassen et al.
Journal of chromatography, 338(1), 113-122 (1985-02-27)
A high-performance liquid chromatographic assay for the determination of isoniazid, acetylisoniazid, acetylhydrazine and diacetylhydrazine (plasma and urine) was developed. The m-chlorobenzoyl derivatives of isoniazid, acetylhydrazine and the internal standard propionylhydrazine were prepared, separated on a RP-18 column and detected at
S V Bhide et al.
Cancer letters, 23(2), 235-240 (1984-06-01)
Two hydrazine derivatives, monoacetyl hydrazine (MAH) and diacetyl hydrazine (DAH), have been tested for mutagenic response in the Salmonella/mammalian microsome assay and micronucleus test. MAH but not DAH, increased the revertant mutants in TA100 and TA1535 and also increased the
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