D97703
Diethyl maleate
97%
Synonym(s):
Maleic acid diethyl ester
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About This Item
Linear Formula:
C2H5OCOCH=CHCOOC2H5
CAS Number:
Molecular Weight:
172.18
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
205-451-9
Beilstein/REAXYS Number:
1100825
MDL number:
Assay:
97%
Form:
liquid
vapor density
5.93 (vs air)
Quality Level
vapor pressure
1 mmHg ( 14 °C)
assay
97%
form
liquid
autoignition temp.
662 °F
refractive index
n20/D 1.441 (lit.)
bp
225 °C (lit.)
mp
−10 °C (lit.)
density
1.064 g/mL at 25 °C (lit.)
SMILES string
CCOC(=O)\C=C/C(=O)OCC
InChI
1S/C8H12O4/c1-3-11-7(9)5-6-8(10)12-4-2/h5-6H,3-4H2,1-2H3/b6-5-
InChI key
IEPRKVQEAMIZSS-WAYWQWQTSA-N
General description
Diethyl maleate is an ester derived from maleic anhydride, used as a building block in the synthesis of pyromellitic acid.
Application
- Retrospective analysis of pesticide metabolites in urine using liquid chromatography coupled to high-resolution mass spectrometry.: This study highlights the use of diethyl maleate in the analysis of pesticide metabolites, demonstrating its application in high-resolution mass spectrometry for detecting urinary pesticide metabolites (Lapez et al., 2016).
- Diethyl maleate inhibits MCA+TPA transformed cell growth via modulation of GSH, MAPK, and cancer pathways.: Research on the inhibition of cancer cell growth by diethyl maleate, focusing on its effects on glutathione, MAPK pathways, and its potential therapeutic applications in cancer treatment (Priya et al., 2014).
- Hepatic transcriptome and proteome responses against diethyl maleate-induced glutathione depletion in the rat.: This study explores the effects of diethyl maleate on liver cells, emphasizing its role in depleting glutathione and its implications for oxidative stress and liver toxicity (Yamauchi et al., 2011).
- Application of the BIRD sandwich for the rapid and accurate determination of (1)H-(1)H NMR coupling constants in higher order spin systems.: This paper discusses the innovative application of diethyl maleate in NMR spectroscopy for accurate determination of coupling constants, enhancing the analysis of complex spin systems (Williamson et al., 2000).
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signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 3 - Eye Irrit. 2 - Skin Sens. 1
Storage Class
10 - Combustible liquids
wgk
WGK 2
flash_point_f
200.1 °F - closed cup
flash_point_c
93.4 °C - closed cup
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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David Guerrero-Gómez et al.
Cell death and differentiation, 26(9), 1545-1565 (2019-02-17)
In the presence of aggregation-prone proteins, the cytosol and endoplasmic reticulum (ER) undergo a dramatic shift in their respective redox status, with the cytosol becoming more oxidized and the ER more reducing. However, whether and how changes in the cellular
Sustainable production of pyromellitic acid with pinacol and diethyl maleate
Yancheng H et al.
Green Chemistry, 19, 1663-1667 (2017)
Lauren Drowley et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 18(10), 1865-1873 (2010-07-29)
Although cellular transplantation has been shown to promote improvements in cardiac function following injury, poor cell survival following transplantation continues to limit the efficacy of this therapy. We have previously observed that transplantation of muscle-derived stem cells (MDSCs) improves cardiac
Global Trade Item Number
| SKU | GTIN |
|---|---|
| D97703-5G | 04061838354068 |
| D97703-100G | 04061833591130 |
| D97703-500G | 04061833591147 |