G11802
2-Guanidinobenzimidazole
95%
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About This Item
Empirical Formula (Hill Notation):
C8H9N5
CAS Number:
Molecular Weight:
175.19
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
226-527-8
MDL number:
Assay:
95%
InChI key
JJWCTKUQWXYIIU-UHFFFAOYSA-N
InChI
1S/C8H9N5/c9-7(10)13-8-11-5-3-1-2-4-6(5)12-8/h1-4H,(H5,9,10,11,12,13)
SMILES string
NC(=N)Nc1nc2ccccc2[nH]1
assay
95%
mp
242-244 °C (dec.) (lit.)
Quality Level
Related Categories
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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S Friis et al.
The Journal of membrane biology, 184(3), 291-297 (2002-03-14)
In this communication we show that Gd3+ acts as an activator of the apical sodium channel (ENaC) in frog skin epithelia. Application of Gd3+ to the apical solution of frog skin epithelia increased the Na+ absorption measured as the amiloride-inhibitable
P Komwatana et al.
The Journal of membrane biology, 162(3), 225-232 (1998-05-16)
We have previously shown that epithelial Na+ channels in mouse mandibular gland duct cells are controlled by cytosolic Na+ and Cl-, acting, respectively, via Go and Gi proteins. Since we found no evidence for control of epithelial Na+ channels by
M Fronius et al.
The Journal of membrane biology, 195(1), 43-51 (2003-09-23)
In the present study we investigated the effect of extracellular gadolinium on amiloride-sensitive Na(+) current across Xenopus alveolar epithelium by Ussing chamber experiments and studied its direct effect on epithelial Na(+) channels with the patch-clamp method. As observed in various
Voltage-gated proton channels from fungi highlight role of peripheral regions in channel activation.
Chang Zhao et al.
Communications biology, 4(1), 261-261 (2021-02-28)
Here, we report the identification and characterization of the first proton channels from fungi. The fungal proteins are related to animal voltage-gated Hv channels and are conserved in both higher and lower fungi. Channels from Basidiomycota and Ascomycota appear to
A Pinelli et al.
Arzneimittel-Forschung, 34(8), 890-894 (1984-01-01)
In this study 2-guanidinebenzimidazole (GBI) and 1-phenylbiguanide (PBG) appear to be capable of decreasing gastric acid secretion, while the compounds dimethylbiguanide and cyanoguanidine do not. Thus, the antisecretory effect is present when the biguanide groups are associated with lipophilic molecules.
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