I2606
3-Indazolinone
97%
Synonym(s):
3-Hydroxy-1H-indazole
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About This Item
Empirical Formula (Hill Notation):
C7H6N2O
CAS Number:
Molecular Weight:
134.14
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
230-904-2
Beilstein/REAXYS Number:
3733
MDL number:
Assay:
97%
InChI key
SWEICGMKXPNXNU-UHFFFAOYSA-N
InChI
1S/C7H6N2O/c10-7-5-3-1-2-4-6(5)8-9-7/h1-4H,(H2,8,9,10)
SMILES string
O=C1NNc2ccccc12
assay
97%
mp
250-252 °C (lit.)
Gene Information
rat ... Alox5(25290)
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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S D Wyrick et al.
Journal of medicinal chemistry, 27(6), 768-772 (1984-06-01)
The apparent benefit of limiting serum cholesterol and triglyceride levels either by dietary restriction or drug therapy has prompted work in our laboratories toward development of a suitable antihyperlipidemic agent. We have demonstrated the antihyperlipidemic activity of a series of
G E Demas et al.
Molecular medicine (Cambridge, Mass.), 3(9), 610-616 (1997-11-05)
Mice with targeted disruption of the gene for the neuronal isoform of nitric oxide synthase (nNOS) display exaggerated aggression. Behavioral studies of mice with targeted gene deletions suffer from the criticism that the gene product is missing not only during
Pedro González-Naranjo et al.
Bioorganic & medicinal chemistry, 28(19), 115672-115672 (2020-09-12)
Synthesis and pharmacological evaluation of a new series of cannabinoid receptor antagonists of indazole ether derivatives have been performed. Pharmacological evaluation includes radioligand binding assays with [3H]-CP55940 for CB1 and CB2 receptors and functional activity for cannabinoid receptors on isolated
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