L032000
DCI Activator
0.25 M
Synonym(s):
DCI activator solution
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About This Item
NACRES:
NA.21
UNSPSC Code:
41116105
Quality Level
product line
Proligo Reagents
form
liquid
storage condition
dry at room temperature
concentration
29-32 g/L (DCI content, titration)
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General description
Activator solution, containing powerful activators like 4,5-dicyanoimidazole(DCI), 5-(3,5-bis(trifluoromethyl)phenyl)-1H-tetrazole (Activator 42) or5-(Ethylthio)-1H-tetrazole (ETT) in acetonitrile, are mixed with solutions ofphosphoramidites during the extension step. The activator reacts with theamidite group to form a highly reactive intermediate. The intermediate thenforms an internucleotide bond with the detritylated 5′hydroxyl group of thegrowing oligonucleotide chain.
Preparation Note
Dicyanoimidazole / Acetonitrile 3/100 (w/v)
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
3 - Flammable liquids
wgk
WGK 3
flash_point_f
41.0 °F
flash_point_c
5 °C
Regulatory Information
危险化学品
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