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Merck
CN

L032100

DCI Activator

0.5 M

Synonym(s):

DCI activator solution

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About This Item

NACRES:
NA.21
UNSPSC Code:
41116105
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Quality Level

type

for DNA synthesis

product line

Proligo Reagents

storage condition

dry at room temperature

concentration

58-64 g/L (DCI content, titration)

impurities

≤30 ppm water content (Karl Fischer)

color

clear

General description

Activator solution, containing powerful activators like 4,5-dicyanoimidazole(DCI), 5-(3,5-bis(trifluoromethyl)phenyl)-1H-tetrazole (Activator 42) or5-(Ethylthio)-1H-tetrazole (ETT) in acetonitrile, are mixed with solutions ofphosphoramidites during the extension step. The activator reacts with theamidite group to form a highly reactive intermediate. The intermediate thenforms an internucleotide bond with the detritylated 5′hydroxyl group of thegrowing oligonucleotide chain.

Preparation Note

Dicycanoimidazole /Acetonitrile 6/100 (w/v)


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signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

41.0 °F

flash_point_c

5 °C

Regulatory Information

危险化学品

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Global Trade Item Number

SKUGTIN
L032100-4X2.5L04061838215833