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L134

Linopirdine

≥98% (HPLC)

Synonym(s):

1,3-Dihydro-1-phenyl-3,3-bis(4-pyridinylmethyl)-2H-indol-2-one, DuP 996

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About This Item

Empirical Formula (Hill Notation):
C26H21N3O
CAS Number:
105431-72-9
Molecular Weight:
391.46
NACRES:
NA.22
PubChem Substance ID:
57654323
UNSPSC Code:
12352100
MDL number:
MFCD00867216
Assay:
≥98% (HPLC)
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Quality Segment

100

assay

≥98% (HPLC)

color

white to off-white

solubility

DMSO: >10 mg/mL, ethanol: 240 mg/mL

SMILES string

O=C1N(c2ccccc2)c3ccccc3C1(Cc4ccncc4)Cc5ccncc5

InChI

1S/C26H21N3O/c30-25-26(18-20-10-14-27-15-11-20,19-21-12-16-28-17-13-21)23-8-4-5-9-24(23)29(25)22-6-2-1-3-7-22/h1-17H,18-19H2

InChI key

YEJCDKJIEMIWRQ-UHFFFAOYSA-N

Gene Information

rat ... Kcnj1(24521)

General description

Linopiridine is a class of drugs that activates the nervous system and enhances the acetylcholine (Ach) in the brain. It can be prepared by reacting oxiindole with 4-picolyl chloride hydrochloride in the presence of a KF-Al2O3 catalyst.

Biochem/physiol Actions

Stimulates release of acetylcholine and other neurotransmitters; cognitive enhancer.

Legal Information

Sold under exclusive license from DuPont.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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