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P1659

Pelargonidin chloride

Name: Pelargonidin chloride
Brand: ALDRICH

Synonym(s):

3,4′,5,7-Tetrahydroxyflavylium chloride, 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-1-benzopyrylium chloride, Pelargonidol chloride

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About This Item

Empirical Formula (Hill Notation):

C₁₅H₁₁ClO₅

CAS Number:

134-04-3

Molecular Weight:

306.70

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

57654503

EC Number:

205-127-7

Beilstein/REAXYS Number:

3922945

MDL number:

MFCD00017589

Form:

powder

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Properties

form

powder

Quality Level

200

storage temp.

2-8°C

SMILES string

[Cl-].Oc1ccc(cc1)-c2[o+]c3cc(O)cc(O)c3cc2O

InChI

1S/C15H10O5.ClH/c16-9-3-1-8(2-4-9)15-13(19)7-11-12(18)5-10(17)6-14(11)20-15;/h1-7H,(H3-,16,17,18,19);1H

InChI key

YPVZJXMTXCOTJN-UHFFFAOYSA-N

Description

Application

Involved in pharmacological studies investigating the use of flavonoids as inhibitors of CD38

Antioxidant and anthocyanidin:

Found in various natural sources evaluated for inhibitory effects on colon and liver cancer cells
Used as hyroperoxide and hydrogen peroxide scavenging substance
Used to study relationship between structure, antioxidant capacity and redox potentials
Studied to determine the mechanism of radical-scavenging

Biochem/physiol Actions

Antioxidant and anthocyanidin.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number

0000549857

0000496623

0000481535

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Articles

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

膳食抗氧化剂

抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子（如铁、铜和镉）引起的氧化损伤。

Luteolin Shifts Oxaliplatin-Induced Cell Cycle Arrest at G₀/G₁ to Apoptosis in HCT116 Human Colorectal Carcinoma Cells.

Chan Ho Jang et al.

Nutrients, 11(4) (2019-04-17)

Certain antioxidative flavonoids are known to activate nuclear factor E2-related factor 2 (Nrf2), a transcription factor that regulates cellular antioxidants and detoxifying response and is reportedly highly activated in many types of cancers. Few studies on the potential undesired effects

Strawberry anthocyanins are recovered in urine as glucuro- and sulfoconjugates in humans.

Catherine Felgines et al.

The Journal of nutrition, 133(5), 1296-1301 (2003-05-06)

Anthocyanins are phenolic compounds widely distributed in fruits and vegetables. Their consumption has been shown to prevent some chronic diseases. Anthocyanin metabolism, however, is still not fully understood. The aim of this work was to evaluate the bioavailability of anthocyanins

Pelargonidin improves memory deficit in amyloid β25-35 rat model of Alzheimer's disease by inhibition of glial activation, cholinesterase, and oxidative stress.

Hamid Sohanaki et al.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 83, 85-91 (2016-10-25)

Alzheimer's disease (AD) is a multifactorial disorder with devastating outcomes and few mostly palliative available therapeutic strategies. Pelargonidin (Pel), an anthocyanin compound, is an estrogen receptor agonist with lower side effects versus estrogen. This study examined neuroprotective effect of Pel

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Global Trade Item Number

SKU	GTIN
P1659-5MG	04061834356042
P1659-10MG	04061822703681