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P2139

Poly(ethylene glycol)

Name: Poly(ethylene glycol)
Brand: ALDRICH

average mol wt 8,000, powder

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Synonym(s):

PEG

Linear Formula:

H(OCH₂CH₂)_nOH

CAS Number:

25322-68-3

MDL number:

MFCD00081839

PubChem Substance ID:

24898275

NACRES:

NA.23

form

powder

mol wt

average mol wt 8,000

solubility

water: soluble (PEG is soluble in water approximately 630 mg/ml, 20 °C)

density

1.0845 g/mL at 70 °C
1.0689 g/mL at 90 °C

Ω-end

hydroxyl

α-end

hydroxyl

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Polyethylene Glycol (PEGs and PEOs)

General description

Polyethylene glycol (PEG) is a hydrophilic polymer. It can be easily synthesized by the anionic ring opening polymerization of ethylene oxide, into a range molecular weights and variety of end groups. When crosslinked into networks PEG can have high water content, forming “hydrogels”. PEG is a suitable material for biological applications because it does not trigger an immune response

Application

Poly (ethylene glycol) can be used in the formulation of the drug to improve its dissolution rate and oral bioavailability.

PEG can be used for the effective isolation of edible nanoparticles (ENPs) which have excellent anti-cancer and anti-inflammatory activities. PEG is a crowding agent and forms a net-like mesh in which nanovesicles are trapped and precipitated. For example, ginger-derived ENPs are isolated using a PEG-based method which is cost-effective compared to ultracentrifugation.

PEG can be used as a precursor to synthesize degradable hydrogels for the controlled release of hydrophilic and high molecular weight pharmaceuticals.

Features and Benefits

Highstructural flexibility
Biocompatibility
Amphiphilicity
Highhydration capacity
Devoidof any steric hindrance

related product

Product No.

Description

Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Consistent and fast inhibition of colon carcinogenesis by polyethylene glycol in mice and rats given various carcinogens.

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Heterologous expression of Arabidopsis thaliana rty gene in strawberry (Fragaria × ananassa Duch.) improves drought tolerance.

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Microdissected "cuboids" for microfluidic drug testing of intact tissues.

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Leslie Y Beh et al.

Cell, 177(7), 1781-1796 (2019-05-21)

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