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P40506

N-Phthaloylglycine

Name: <I>N</I>-Phthaloylglycine
Brand: ALDRICH

97%

Synonym(s):

1,3-Dioxo-2-isoindolineacetic acid, Phthalimidoacetic acid

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About This Item

Empirical Formula (Hill Notation):

C₁₀H₇NO₄

CAS Number:

4702-13-0

Molecular Weight:

205.17

NACRES:

NA.22

PubChem Substance ID:

24898488

eCl@ss:

32160406

UNSPSC Code:

12352209

EC Number:

225-177-3

MDL number:

MFCD00005900

Beilstein/REAXYS Number:

184174

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Properties

Quality Level

100

assay

97%

form

powder or crystals

reaction suitability

reaction type: solution phase peptide synthesis

color

white

mp

193-196 °C (lit.)

SMILES string

OC(=O)CN1C(=O)c2ccccc2C1=O

InChI

1S/C10H7NO4/c12-8(13)5-11-9(14)6-3-1-2-4-7(6)10(11)15/h1-4H,5H2,(H,12,13)

InChI key

WQINSVOOIJDOLJ-UHFFFAOYSA-N

Description

pictograms

GHS07

signalword

Warning

hcodes

H319

pcodes

P264 - P280 - P305 + P351 + P338 - P337 + P313

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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N-phthaloyl-glycine-hydroxamic acid as serum iron chelator in rats.

Julija Matijević-Sosa et al.

Acta pharmaceutica (Zagreb, Croatia), 58(2), 231-236 (2008-06-03)

The aim of this study was to investigate the activity of N-phthaloyl-glycine-hydroxamic acid (Phth-Gly-HA) as a new iron chelator in vivo to be used in iron overload diseases. After intraperitoneal application of Phth-Gly-HA to male rats (1 mg kg(-1) body

Comparative pharmacokinetic and pharmacodynamic analysis of phthaloyl glycine derivatives with potential antiepileptic activity.

O abu Salach et al.

Pharmaceutical research, 11(10), 1429-1434 (1994-10-01)

Glycine, in addition to GABA, is one of the most important neurotransmitter amino acids. The described structure pharmacokinetic pharmacodynamic relationships (SPPR) study explored the possibility of utilizing phthaloyl derivatives of glycine as new antiepileptics. This was carried out by investigating

Synthesis, crystal structure, DNA binding and in vitro biological studies of Ni(II), Cu(II) and Zn(II) complexes of N-phthaloylglycine.

Nasima Arshad et al.

Journal of photochemistry and photobiology. B, Biology, 117, 228-239 (2012-11-20)

Ni(II), Cu(II) and Zn(II) metal complexes of N-phthaloylglycine were synthesized, characterized, reported for single crystal X-ray diffraction analysis for Ni(II) complex, and investigated for their binding with DNA under physiological conditions, using spectroscopic (UV-visible and fluorescence) and hydrodynamic techniques. Experimental

Global Trade Item Number

SKU	GTIN
P40506-100G	04061832649481
P40506-25G	04061834373537