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About This Item
Empirical Formula (Hill Notation):
C17H19NO3
CAS Number:
Molecular Weight:
285.34
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
202-348-0
Beilstein/REAXYS Number:
90741
MDL number:
Assay:
≥97%
Form:
crystalline, powder, crystals or chunks, solid
Quality Level
assay
≥97%
form
crystalline, powder, crystals or chunks, solid
mp
131-135 °C (lit.)
SMILES string
O=C(\C=C\C=C\c1ccc2OCOc2c1)N3CCCCC3
InChI
1S/C17H19NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h2-3,6-9,12H,1,4-5,10-11,13H2/b6-2+,7-3+
InChI key
MXXWOMGUGJBKIW-YPCIICBESA-N
Gene Information
human ... CYP3A4(1576)
Application
Reactant for synthesis of:
- Dimeric amide alkaloids
- Piperoyl-amino acid conjugates used for antileishmanial activity
- Piperine derived amides with TRPV1 activity
- Piperine analogues as S. aureus NorA efflux pump inhibitors
- Bioactive conjugates of curcumin with antimicrobial and antiproliferative properties
- Piperine derivatives for use as trypanocidal agents
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 2
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
涉药品监管产品
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Jiu-Wang Yu et al.
Molecular diversity, 25(1), 233-248 (2020-03-05)
Piperine is the main active component of Piper longum L., which is also the main component of anti-sciatica Mongolian medicine Naru Sanwei pill. It has many pharmacological activities such as anti-inflammatory and immune regulation. This paper aims to preliminarily explore
V. R. S. Rao, et al.,
Tetrahedron, 67, 1885-1892 (2011)
Welisson da Silva Ferreira et al.
Bioorganic & medicinal chemistry, 16(6), 2984-2991 (2008-01-30)
We herein describe the synthesis and characterization of nine new 1,3,4-thiadiazolium-2-phenylamine chlorides derived from natural piperine. We evaluate their toxic effects against the different evolutive forms of Trypanosoma cruzi, and the host cell (murine macrophages). The results obtained show that
Global Trade Item Number
| SKU | GTIN |
|---|---|
| P49007-1G | 04061834375333 |
| P49007-5G | 04061834375364 |

