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QBD10262

m-dPEG®12-NHS ester

Synonym(s):

Polyethylene glycol

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About This Item

Empirical Formula (Hill Notation):
C30H55NO16
Molecular Weight:
685.75
UNSPSC Code:
12352108
PubChem Substance ID:
329823902
NACRES:
NA.22
MDL number:
MFCD13184970
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assay

>90%

form

solid or viscous liquid

reaction suitability

reagent type: chemical modification reagent, reagent type: cross-linking reagent
reactivity: amine reactive

polymer architecture

shape: linear
functionality: monofunctional

shipped in

ambient

storage temp.

−20°C

SMILES string

COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O

InChI

1S/C30H55NO16/c1-35-6-7-37-10-11-39-14-15-41-18-19-43-22-23-45-26-27-46-25-24-44-21-20-42-17-16-40-13-12-38-9-8-36-5-4-30(34)47-31-28(32)2-3-29(31)33/h2-27H2,1H3

InChI key

ZMXRHHJWXLKMTL-UHFFFAOYSA-N

Features and Benefits

The m-dPEG®12-NHS ester provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG® molecules are hydrophilic and non-immunogenic of exact length. Modification with m-dPEG® reagents can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG®12-NHS (N-hydroxysuccinimide) ester reacts with amines.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

Storage Class

11 - Combustible Solids

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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