QBD10513
Azido-dPEG®12-acid
别名:
Polyethylene glycol, alpha-(2-azidoethyl)-omega-(2-carboxyethoxy)poly(oxy-1,2-ethanediyl)
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关于此项目
经验公式（希尔记法）:
C27H53N3O14
化学文摘社编号:
分子量:
643.72
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.22
MDL number:
assay
>90%
form
solid or viscous liquid
reaction suitability
reaction type: click chemistry, reagent type: cross-linking reagent
reaction type: click chemistry
polymer architecture
shape: linear
functionality: heterobifunctional
shipped in
ambient
storage temp.
−20°C
SMILES string
OC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O
InChI
1S/C27H53N3O14/c28-30-29-2-4-34-6-8-36-10-12-38-14-16-40-18-20-42-22-24-44-26-25-43-23-21-41-19-17-39-15-13-37-11-9-35-7-5-33-3-1-27(31)32/h1-26H2,(H,31,32)
InChI key
DYFODOGACDHUBQ-UHFFFAOYSA-N
Features and Benefits
The azido-dPEG®12 contains an azide function on one end of a single molecular weight dPEG® spacer (46.4 Å) and a reactive group on the other end of the spacer. The dPEG® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. The reactive acid functional group may be activated with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) or N,N′-dicyclohexylcarbodiimide (DCC) for conjugation to an amine. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.
Legal Information
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable