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QBD10525

Azido-dPEG®23-amine

Synonym(s):

Polyethylene glycol

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About This Item

Empirical Formula (Hill Notation):
C48H98N4O23
Molecular Weight:
1099.30
UNSPSC Code:
12352116
PubChem Substance ID:
329823939
NACRES:
NA.22
MDL number:
MFCD18427349
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assay

>90%

form

solid or viscous liquid

reaction suitability

reaction type: click chemistry, reagent type: cross-linking reagent
reaction type: click chemistry

polymer architecture

shape: linear
functionality: heterobifunctional

shipped in

ambient

storage temp.

−20°C

SMILES string

NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]

InChI

1S/C48H98N4O23/c49-1-3-53-5-7-55-9-11-57-13-15-59-17-19-61-21-23-63-25-27-65-29-31-67-33-35-69-37-39-71-41-43-73-45-47-75-48-46-74-44-42-72-40-38-70-36-34-68-32-30-66-28-26-64-24-22-62-20-18-60-16-14-58-12-10-56-8-6-54-4-2-51-52-50/h1-49H2

InChI key

MUYDHNADYGGZNC-UHFFFAOYSA-N

General description

Azido-dPEG®23-amine is a biocompatible crosslinking reagent used in copper(I)/ruthenium catalyzed, and strain-promoted click chemistry reactions.

Features and Benefits

The azido-dPEG®23-amine contains an azide function on one end of a single molecular weight dPEG® spacer (86.8 Å) and a reactive group on the other end of the spacer. The dPEG® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. The primary amine reacts with acids and active esters. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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