QBD10745
m-dPEG®4-MAL
Synonym(s):
Polyethylene glycol
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About This Item
Empirical Formula (Hill Notation):
C16H26N2O7
CAS Number:
Molecular Weight:
358.39
UNSPSC Code:
51171641
PubChem Substance ID:
NACRES:
NA.22
MDL number:
assay
>90%
form
solid or viscous liquid
reaction suitability
reactivity: thiol reactive, reagent type: chemical modification reagent, reagent type: cross-linking reagent
reactivity: sulfhydryl reactive
polymer architecture
shape: linear
functionality: monofunctional
shipped in
ambient
storage temp.
−20°C
SMILES string
O=C1C=CC(N1CCC(NCCOCCOCCOCCOC)=O)=O
InChI key
DOHTYEHHGXSUJO-UHFFFAOYSA-N
Features and Benefits
The m-dPEG®4-MAL provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG® molecules are hydrophilic and non-immunogenic of exact length. Modification with m-dPEG® reagents can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG®4-MAL reacts with free sulfhydryls in a rapid, highly specific reaction in aqueous media at pH 6.5-7.5.
Legal Information
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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