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Merck
CN

QBD10866

SPDP-dPEG®36-acid

>95% (HPLC)

别名:

OPSS-PEG1500-acid, OPSS-PEG36-acid, SPDP-PEG-acid, SPDP-PEG36-COOH, SPDP-PEG36-acid

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关于此项目

经验公式(希尔记法):
C83H158N2O39S2
分子量:
1872.26
UNSPSC Code:
12352106
NACRES:
NA.22
MDL number:
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assay

>95% (HPLC)

form

solid or viscous liquid

reaction suitability

reaction type: Pegylations

polymer architecture

shape: linear
functionality: heterobifunctional

shipped in

ambient

storage temp.

−20°C

SMILES string

S(Sc1ncccc1)CCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O

InChI

1S/C83H158N2O39S2/c86-81(5-80-125-126-82-3-1-2-6-85-82)84-7-9-90-11-13-92-15-17-94-19-21-96-23-25-98-27-29-100-31-33-102-35-37-104-39-41-106-43-45-108-47-49-110-51-53-112-55-57-114-59-61-116-63-65-118-67-69-120-71-73-122-75-77-124-79-78-123-76-74-121-72-7

InChI key

YETQZNCXLDFCHR-UHFFFAOYSA-N

Features and Benefits

SPDP-dPEG36-acid is a crosslinking reagent designed to conjugate free amines and sulfhydryls. The single molecular weight (i.e., monodispersed) PEG crossbridge between the two functional groups is 115 atoms (137.8 Å) long. Using a suitable carbodiimide, such as EDC, the propionic acid group reacts with free primary amines to form amide bonds. The pyridyl disulfide (SPDP, also known as OPSS) functional group reacts with free thiols to form disulfide bonds. This product is useful for crosslinking peptides, proteins, and small molecules, and modifying surfaces with suitable reactive sites. SPDP-dPEG36-acid is a monodisperse equivalent of the polymeric PEG1500.

Legal Information

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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