QBD10866
SPDP-dPEG®36-acid
>95% (HPLC)
别名:
OPSS-PEG1500-acid, OPSS-PEG36-acid, SPDP-PEG-acid, SPDP-PEG36-COOH, SPDP-PEG36-acid
SMILES string
S(Sc1ncccc1)CCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O
InChI
1S/C83H158N2O39S2/c86-81(5-80-125-126-82-3-1-2-6-85-82)84-7-9-90-11-13-92-15-17-94-19-21-96-23-25-98-27-29-100-31-33-102-35-37-104-39-41-106-43-45-108-47-49-110-51-53-112-55-57-114-59-61-116-63-65-118-67-69-120-71-73-122-75-77-124-79-78-123-76-74-121-72-7
InChI key
YETQZNCXLDFCHR-UHFFFAOYSA-N
assay
>95% (HPLC)
form
solid or viscous liquid
reaction suitability
reaction type: Pegylations
polymer architecture
shape: linear
functionality: heterobifunctional
shipped in
ambient
storage temp.
−20°C
Features and Benefits
SPDP-dPEG36-acid is a crosslinking reagent designed to conjugate free amines and sulfhydryls. The single molecular weight (i.e., monodispersed) PEG crossbridge between the two functional groups is 115 atoms (137.8 Å) long. Using a suitable carbodiimide, such as EDC, the propionic acid group reacts with free primary amines to form amide bonds. The pyridyl disulfide (SPDP, also known as OPSS) functional group reacts with free thiols to form disulfide bonds. This product is useful for crosslinking peptides, proteins, and small molecules, and modifying surfaces with suitable reactive sites. SPDP-dPEG36-acid is a monodisperse equivalent of the polymeric PEG1500.
Legal Information
Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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