S3003
Sesamol
98%
Synonym(s):
3,4-(Methylenedioxy)phenol, 5-Benzodioxolol
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About This Item
Empirical Formula (Hill Notation):
C7H6O3
CAS Number:
Molecular Weight:
138.12
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
208-561-5
Beilstein/REAXYS Number:
127405
MDL number:
Assay:
98%
InChI key
LUSZGTFNYDARNI-UHFFFAOYSA-N
InChI
1S/C7H6O3/c8-5-1-2-6-7(3-5)10-4-9-6/h1-3,8H,4H2
SMILES string
Oc1ccc2OCOc2c1
assay
98%
mp
62-65 °C (lit.)
Quality Level
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Related Categories
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Tian Yuan et al.
Journal of agricultural and food chemistry, 67(22), 6190-6201 (2019-05-24)
Sesamol, an antioxidant lignan from sesame oil, possesses neuroprotective bioactivities. The present work was aimed to elucidate the systemic protective effects of sesamol on cognitive deficits and to determine the possible link between gut and brain. Wildtype and ApoE-/- mice
Soheila Kashanian et al.
Molecular biology reports, 40(2), 1173-1179 (2012-10-17)
The interaction of native calf thymus DNA (CT-DNA) with sesamol (3,4-methylenedioxyphenol) in Tris-HCl buffer at neutral pH 7.4 was monitored by absorption spectrophotometry, viscometry and spectrofluorometry. It is found that sesamol molecules could interact with DNA outside and/or groove binding
Yung-Chang Lu et al.
Journal of agricultural and food chemistry, 59(9), 4969-4978 (2011-03-25)
Overexpression of matrix metalloproteinases (MMPs) is a major pathological factor causing cartilage destruction in osteoarthritis (OA). This study aimed to investigate the effects and mechanisms of sesamol on expression of MMPs in activated chondrosarcoma cells. Sesamol significantly attenuated TNF-α- and
S Ramachandran et al.
Archives of dermatological research, 302(10), 733-744 (2010-08-11)
The exposure of cells to ultraviolet B radiation (UVB) can induce the production of reactive oxygen species (ROS) which damage cellular components. Free radical scavengers and antioxidants can interfere with the production of ROS. We studied cytotoxicity, intracellular ROS levels
Victor Raj Mohan Chandrasekaran et al.
Human & experimental toxicology, 30(10), 1609-1615 (2011-01-18)
3,4-Methylenedioxyphenol (sesamol) is effective against acetaminophen-induced liver injury in rats. Whether sesamol's anti-hepatotoxic effect is comparable to that of N-acetylcysteine has never been studied. We investigated the anti-hepatotoxic effects of sesamol and N-acetylcysteine on acetaminophen-induced hepatotoxicity in mice. Equimolar doses
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