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Merck
CN

T12653

Tetrahydrofurfuryl alcohol

98%

Synonym(s):

Oxolan-2-yl methanol, THFA, NSC 15434, Tetrahydro-2-furanmethanol

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About This Item

Empirical Formula (Hill Notation):
C5H10O2
CAS Number:
Molecular Weight:
102.13
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
202-625-6
Beilstein/REAXYS Number:
102723
MDL number:
Assay:
98%
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Product Name

Tetrahydrofurfuryl alcohol, 98%

InChI key

BSYVTEYKTMYBMK-UHFFFAOYSA-N

InChI

1S/C5H10O2/c6-4-5-2-1-3-7-5/h5-6H,1-4H2

SMILES string

OCC1CCCO1

vapor density

3.52 (vs air)

vapor pressure

2.3 mmHg ( 39 °C)

assay

98%

expl. lim.

9.7 %

refractive index

n20/D 1.452 (lit.)

bp

178 °C (lit.)

mp

−80 °C (lit.)

density

1.054 g/mL at 25 °C (lit.)

Quality Level

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Application

  • Tetrahydrofurfuryl alcohol (THFA) is a solvent modifier for sodium borohydride used in enantioselective reduction of aromatic imines or ketones to the corresponding alcohols.
  • It can be used to synthesize tetrahydrofurfuryl acetate, tetrahydrofurfuryl propionate and tetrahydrofurfuryl butyrate, which are used as flavoring agents in food industry.
  • Application of THFA as a solvent for water-based colorants; coupling solvent for agricultural formulations such as pesticides, fungicides and herbicides; plasticizer for paints and varnishes are reported.

General description

Tetrahydrofurfuryl alcohol is a non-carcinogenic, biodegradable, protic solvent.

pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

163.4 °F - closed cup

flash_point_c

73 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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CLH report: `Tetrahydrofurfuryl alcohol (THFA)?.
unpublished (2011)
Encyclopedia of food & color additives.
Encyclopedia of Food and Color Additives (1996)
Fenaroli's handbook of flavor ingredients.
Fenaroli's Handbook of Flavor Ingredients (2016)
Enantioselective borohydride reduction catalyzed by optically active cobalt complexes.
Yamada T, et al.
Chemistry?A European Journal , 9(18), 4485-4509 (2003)
Encyclopedia of food & color additives.
Encyclopedia of Food and Color Additives (1996)

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