T45802
2,4,6-Triaminopyrimidine
97%
Synonym(s):
2,4,6-Pyrimidinetriamine
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About This Item
Empirical Formula (Hill Notation):
C4H7N5
CAS Number:
Molecular Weight:
125.13
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
213-720-7
Beilstein/REAXYS Number:
118448
MDL number:
Product Name
2,4,6-Triaminopyrimidine, 97%
InChI key
JTTIOYHBNXDJOD-UHFFFAOYSA-N
InChI
1S/C4H7N5/c5-2-1-3(6)9-4(7)8-2/h1H,(H6,5,6,7,8,9)
SMILES string
Nc1cc(N)nc(N)n1
assay
97%
mp
249-251 °C (lit.)
Quality Level
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Related Categories
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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W L Armarego et al.
The Biochemical journal, 211(2), 357-361 (1983-05-01)
The Km and kcat. values for [6,6,7,7-2H]7,8(6H)-dihydropterin and 2,6-diamino-5-iminopyrimidin-4-one were determined for dihydropteridine reductase (EC 1.6.99.10) from two sources. The parameters of the pterin are of the same order as those of the most effective substrates of dihydropteridine reductase. The
The effect of electrical gradients on current fluctuations and impedance recorded from Necturus gallbladder.
H Gögelein et al.
The Journal of membrane biology, 60(3), 199-209 (1981-01-01)
Chris M Wood et al.
The Journal of experimental biology, 215(Pt 3), 508-517 (2012-01-17)
Paracellular permeability and absorptive water flux across the intestine of the euryhaline killifish were investigated using in vitro gut sac preparations from seawater- and freshwater-acclimated animals. The permeability of polyethylene glycol (PEG), a well-established paracellular probe, was measured using trace
M P Vinardell et al.
Revista espanola de fisiologia, 39(2), 193-196 (1983-06-01)
D-glucose diffusion in both jejunum and ileum using a perfusion system in vivo was determined. 2,4,6-triaminopyrimidine (20 mM) induced an inhibition on D-glucose diffusion of 32% in the two segments of the small intestine studied. Glucose net efflux from the
R Soni et al.
Journal of the National Cancer Institute, 93(6), 436-446 (2001-03-22)
Cyclin-dependent kinase 4 (Cdk4) represents a prime target for the treatment of cancer because most human cancers are characterized by overexpression of its activating partner cyclin D1, loss of the natural Cdk4-specific inhibitor p16, or mutation(s) in Cdk4's catalytic subunit.
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