Merck
CN
All Photos(1)

Documents

Safety Information

W271004

Sigma-Aldrich

Methyl 4-hydroxybenzoate

≥99%, FCC

Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
p-Hydroxybenzoic acid methyl ester, Methyl paraben, NIPAGIN
Linear Formula:
HOC6H4CO2CH3
CAS Number:
99-76-3
Molecular Weight:
152.15
FEMA Number:
2710
Beilstein:
509801
EC Number:
202-785-7
Council of Europe no.:
657c
MDL number:
MFCD00002352
PubChem Substance ID:
24901279
NACRES:
NA.21

biological source

synthetic

Quality Level

400

grade

Fragrance grade
Kosher

Agency

follows IFRA guidelines

reg. compliance

EU Regulation 1223/2009
FCC
FDA 21 CFR 172.515

Assay

≥99%

mp

125-128 °C (lit.)

application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

food allergen

no known allergens

fragrance allergen

no known allergens

Organoleptic

odorless

SMILES string

COC(=O)c1ccc(O)cc1

InChI

1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3

InChI key

LXCFILQKKLGQFO-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Methyl 4-hydroxybenzoate is commonly used as an antimicrobial preservative in foods, drugs and cosmetics. It occurs naturally in Securidaca longepedunculata Fers roots.

Disclaimer

For R&D or non-EU Food use. Not for retail sale.

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

Pictograms

Environment
GHS09

Hazard Statements

H411

Precautionary Statements

P273 - P391 - P501

Hazard Classifications

Aquatic Chronic 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

334.4 °F

Flash Point(C)

168 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

新产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Evaluation of the health aspects of methyl paraben: a review of the published literature.
Soni MG, et al.
Food And Chemical Toxicology, 40(10, 1335-1373 (2002)
Essential oils of Nigeria II: analysis of the leaf oil of Securidaca longependuculata Fers.
Adebayo MA, et al.
J. Essent. Oil Res., 19(5, 452-454 (2007)
Kate Hoffman et al.
Environment international, 119, 26-36 (2018-06-22)
Semi-volatile organic compounds (SVOCs) are used extensively in consumer and personal care products; electronics; furniture; and building materials and are detected in most indoor environments. As a result, human exposure to mixtures of SVOCs is wide-spread. However, very few studies
Raena Morley et al.
Journal of chromatography. A, 1501, 26-38 (2017-05-05)
Trapping multiple dual mode centrifugal partition chromatography (trapping MDM CPC) is an alternative to isocratic pulse injections for the separation of intermediately-eluting components from complex mixtures using liquid-liquid chromatography. In this work, a throughput maximization strategy is developed and validated
Jia Chen et al.
Journal of chromatography. A, 1591, 33-43 (2019-01-21)
A novel supramolecular solvent (SUPRAS) based on hexafluoroisopropanol (HFIP)/Brij-35 was proposed for liquid-phase microextraction (LPME) of parabens in water samples, pharmaceuticals and personal care products. Brij-35 is a cost-effective and non-toxic non-ionic surfactant, but it has a high cloud point
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service