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Merck
CN

W361518

Thiazole

≥99%

Synonym(s):

1,3-thiazole

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About This Item

Empirical Formula (Hill Notation):
C3H3NS
CAS Number:
288-47-1
Molecular Weight:
85.13
FEMA Number:
3615
Council of Europe no.:
11642
UNSPSC Code:
12164502
PubChem Substance ID:
24901810
Flavis number:
15.028
EC Number:
206-021-3
NACRES:
NA.21
MDL number:
MFCD00005315
Beilstein/REAXYS Number:
103852
Organoleptic:
nutty
Grade:
Halal
Kosher
Biological source:
synthetic
Agency:
meets purity specifications of JECFA
Food allergen:
no known allergens

Key Documents

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Product Name

Thiazole, ≥99%

grade

Halal
Kosher

SMILES string

c1cscn1

InChI

1S/C3H3NS/c1-2-5-3-4-1/h1-3H

InChI key

FZWLAAWBMGSTSO-UHFFFAOYSA-N

biological source

synthetic

agency

meets purity specifications of JECFA

assay

≥99%

refractive index

n20/D 1.538 (lit.)

bp

117-118 °C (lit.)

density

1.2 g/mL at 25 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

nutty

Quality Level

300
400

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Disclaimer

For R&D or non-EU Food use. Not for retail sale.

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

hcodes

H225,H302

Hazard Classifications

Acute Tox. 4 Oral - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

71.6 °F - closed cup

flash_point_c

22 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

危险化学品
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Certificates of Analysis (COA)

Lot/Batch Number
SHBS7917
SHBR9679
SHBQ3738
SHBN0755
SHBL4115

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Yukiko Kiniwa et al.
PloS one, 10(5), e0124094-e0124094 (2015-05-21)
Immunotherapy has emerged as a promising strategy for the treatment of metastatic melanoma. Clinical studies have demonstrated the feasibility of cancer immunotherapy using tumor antigens recognized by CD8(+) T cells. However, the overall immune responses induced by these antigens are
Eita Sasaki et al.
Nature, 510(7505), 427-431 (2014-05-13)
Sulphur is an essential element for life and is ubiquitous in living systems. Yet how the sulphur atom is incorporated into many sulphur-containing secondary metabolites is poorly understood. For bond formation between carbon and sulphur in primary metabolites, the major
Mohammad Sayed Alam et al.
Chemical & pharmaceutical bulletin, 62(12), 1259-1268 (2014-12-03)
A novel series of 2-arylidenehydrazinyl-4-arylthiazole analogues (3a-p) was designed and synthesized in excellent yields using a rapid, simple, efficient methodology. Sixteen novel compounds were screened for in vitro antimicrobial activities against eleven bacteria, namely, Staphylococcus aureus, Listeria monocytogenes, Enterococcus faecalis
Maria Hayashi et al.
Journal of nutritional science and vitaminology, 61(3), 270-274 (2015-08-01)
The biosynthetic pathways of the thiazole moiety of thiamin were studied in the archaeon Halobacterium salinarum. Thiamin is generated by the union of 4-amino-5-hydroxymethyl-2-methylpyrimidine (pyrimidine) and 5-(2-hydroxyethyl)-4-methylthiazole (thiazole). The biosynthesis of thiazole is different in facultative anaerobes, aerobes and eukaryotes.
Shruthi Vaidhyanathan et al.
Drug metabolism and disposition: the biological fate of chemicals, 42(8), 1292-1300 (2014-05-31)
Brain metastases are a major cause of mortality in patients with advanced melanoma. Adequate brain distribution of targeted agents for melanoma will be critical for treatment success. Recently, improvement in overall survival led to US Food and Drug Administration (FDA)
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