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Merck
CN

W502707

Succinic acid

FCC

Synonym(s):

Butanedioic acid

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About This Item

Linear Formula:
HOOCCH2CH2COOH
CAS Number:
110-15-6
Molecular Weight:
118.09
PubChem Substance ID:
24902009
UNSPSC Code:
12164502
Council of Europe no.:
24
FEMA Number:
4719
Flavis number:
8.024
EC Number:
203-740-4
MDL number:
MFCD00002789
Beilstein/REAXYS Number:
1754069

Key Documents

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InChI key

KDYFGRWQOYBRFD-UHFFFAOYSA-N

InChI

1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)

SMILES string

OC(=O)CCC(O)=O

biological source

synthetic

grade

Halal, Kosher

reg. compliance

FCC, FDA 21 CFR 184.1091

assay

99.0-100.5% (by NaOH, titration)

form

crystals

bp

235 °C (lit.)

solubility

water: soluble 83 g/L at 25 °C

density

1.564 g/cm3 at 15 °C

cation traces

As: ≤3 ppm, Cd: ≤1 ppm, Hg: ≤1 ppm, Pb: ≤2 ppm

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

acidic; sour

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pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H318

Hazard Classifications

Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
MKBW6322V
MKBT9495V
MKBT1102V
MKBR7018V
MKBR6275V

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James H Marden et al.
Evolution; international journal of organic evolution, 67(4), 1105-1115 (2013-04-05)
Oxygen conductance to the tissues determines aerobic metabolic performance in most eukaryotes but has cost/benefit tradeoffs. Here we examine in lowland populations of a butterfly a genetic polymorphism affecting oxygen conductance via the hypoxia-inducible factor (HIF) pathway, which senses intracellular
José Manuel Otero et al.
PloS one, 8(1), e54144-e54144 (2013-01-26)
Saccharomyces cerevisiae is the most well characterized eukaryote, the preferred microbial cell factory for the largest industrial biotechnology product (bioethanol), and a robust commerically compatible scaffold to be exploitted for diverse chemical production. Succinic acid is a highly sought after
Susan Jahn et al.
Biochimica et biophysica acta, 1833(12), 2879-2889 (2013-07-28)
To investigate a possible role of the nitrogen-PTS (PTS(Ntr)) in controlling carbon metabolism, we determined the growth of Escherichia coli LJ110 and of isogenic derivatives, mutated in components of the PTS(Ntr), on different carbon sources. The PTS(Ntr) is a set
G M Tannahill et al.
Nature, 496(7444), 238-242 (2013-03-29)
Macrophages activated by the Gram-negative bacterial product lipopolysaccharide switch their core metabolism from oxidative phosphorylation to glycolysis. Here we show that inhibition of glycolysis with 2-deoxyglucose suppresses lipopolysaccharide-induced interleukin-1β but not tumour-necrosis factor-α in mouse macrophages. A comprehensive metabolic map
Hilal Taymaz-Nikerel et al.
Metabolic engineering, 16, 115-129 (2013-02-02)
The interactions between the intracellular metabolome, fluxome and growth rate of Escherichia coli after sudden glycolytic/gluconeogenic substrate shifts are studied based on pulses of different substrates to an aerobic glucose-limited steady-state (dilution rate=0.1h(-1)). After each added glycolytic (glucose) and gluconeogenic
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