form
chloroform solution
packaging
pkg of 1 × 4 mL (181104C-100mg), pkg of 5 × 4 mL (181104C-500mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
concentration
25 mg/mL (181104C-100mg), 25 mg/mL (181104C-500mg)
lipid type
lipid extracts
shipped in
dry ice
storage temp.
−20°C
General description
Total Lipid Extract is a chloroform:methanol extract of the respective tissue (Brain, Soybean, Heart, etc.). This extract is partitioned against deionized water, and the chloroform phase is concentrated.
Application
Liver extract total has been used for the identification of cholesterol as an endogenous ligand of human macrophage-inducible C-type lectin (hMincle).
Packaging
5 mL Clear Glass Sealed Ampule (181104C-100mg)
5 mL Clear Glass Sealed Ampule (181104C-500mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
target_organs
Central nervous system, Liver,Kidney
wgk
WGK 3
Storage Class
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
flash_point_f
does not flash
flash_point_c
does not flash
Regulatory Information
易制毒化学品（2类）
危险化学品
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Human Mincle binds to cholesterol crystals and triggers innate immune responses
Kiyotake R, et al.
The Journal of biological chemistry, 290(42), 25322-25332 (2015)
Filip Duša et al.
Biochimica et biophysica acta. Biomembranes, 1862(2), 183115-183115 (2019-11-11)
The cell membrane is mainly composed of lipid bilayers with inserted proteins and carbohydrates. Lipid bilayers made of purified or synthetic lipids are widely used for estimating the effect of target compounds on cell membranes. However, the composition of such
Hari Kiran Kotapati et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1145, 122099-122099 (2020-04-20)
Three normal phase HPLC methods were produced to separate lipid classes on a PVA-Sil stationary phase including: 9 polar lipids (method 1); 13 combined polar and neutral lipids (method 2); and a combined method that further separates the neutral lipids
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 181104C-500MG | 04061835532742 |
| 181104C-100MG | 04061835532735 |