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About This Item
Empirical Formula (Hill Notation):
C30H50O
CAS Number:
Molecular Weight:
426.72
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
description
8,24-lanostadien-3β-ol
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (700063P-1mg), pkg of 1 × 10 mg (700063P-10mg), pkg of 1 × 5 mg (700063P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
SMILES string
O[C@@H]1C([C@H]2[C@](CC1)(C3=C([C@]4([C@@]([C@H](CC4)[C@@H](CCC=C(C)C)C)(CC3)C)C)CC2)C)(C)C
InChI
1S/C30H50O/c1-20(2)10-9-11-21(3)22-14-18-30(8)24-12-13-25-27(4,5)26(31)16-17-28(25,6)23(24)15-19-29(22,30)7/h10,21-22,25-26,31H,9,11-19H2,1-8H3/t21-,22-,25+,26+,28-,29-,30+/m1/s1
InChI key
CAHGCLMLTWQZNJ-BQNIITSRSA-N
General description
Lanosterol is a lanostane-type tetracyclic triterpene, which is the first sterol in lipid biosynthetic pathway.
Biochem/physiol Actions
Lanosterol inhibits cataract formation, prevents lens opacity and reverses crystalline aggregation.
Packaging
5 mL Amber Glass Screw Cap Vial (700063P-10mg)
5 mL Amber Glass Screw Cap Vial (700063P-1mg)
5 mL Amber Glass Screw Cap Vial (700063P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Lanosterol synthase pathway alleviates lens opacity in age-related cortical cataract
Shen X, et al.
Journal of Ophthalmology, 41(4), 744-747 (2018)
Tetracyclic triterpenes from Inonotus obliquus (PERS.) PIL.(CHAGA) growing in Russia
Zhukovich EN, et al.
Pharmaceutical Chemistry Journal, 2018, 495-496 (2010)
Lindsay M Webb et al.
The Journal of clinical investigation, 130(4), 1683-1698 (2020-02-25)
Protein arginine methyltransferase 5 (PRMT5) catalyzes symmetric dimethylation (SDM) of arginine, a posttranslational modification involved in oncogenesis and embryonic development. However, the role and mechanisms by which PRMT5 modulates Th cell polarization and autoimmune disease have not yet been elucidated.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 700063P-1MG | 04061835384730 |
| 700063P-5MG | 04061835384747 |
| 700063P-10MG | 04061835384723 |