产品名称
羊毛甾醇, Avanti Research™ - A Croda Brand
SMILES string
O[C@@H]1C([C@H]2[C@](CC1)(C3=C([C@]4([C@@]([C@H](CC4)[C@@H](CCC=C(C)C)C)(CC3)C)C)CC2)C)(C)C
InChI
1S/C30H50O/c1-20(2)10-9-11-21(3)22-14-18-30(8)24-12-13-25-27(4,5)26(31)16-17-28(25,6)23(24)15-19-29(22,30)7/h10,21-22,25-26,31H,9,11-19H2,1-8H3/t21-,22-,25+,26+,28-,29-,30+/m1/s1
InChI key
CAHGCLMLTWQZNJ-BQNIITSRSA-N
description
8,24-lanostadien-3β-ol
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (700063P-1mg)
pkg of 1 × 10 mg (700063P-10mg)
pkg of 1 × 5 mg (700063P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
Biochem/physiol Actions
羊毛甾醇可抑制白内障形成，防止晶状体混浊，逆转晶体蛋白聚集。
General description
羊毛甾醇是羊毛甾烷型四环三萜，是脂类生物合成途径中的第一种甾醇。
Packaging
5 mL棕色玻璃螺旋盖样品瓶（700063P-10mg）
5 mL棕色玻璃螺旋盖样品瓶（700063P-1mg）
5 mL棕色玻璃螺旋盖样品瓶（700063P-5mg）
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
wgk
WGK 1
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
Lanosterol synthase pathway alleviates lens opacity in age-related cortical cataract
Shen X, et al.
Journal of Ophthalmology, 41(4), 744-747 (2018)
Tetracyclic triterpenes from Inonotus obliquus (PERS.) PIL.(CHAGA) growing in Russia
Zhukovich EN, et al.
Pharmaceutical Chemistry Journal, 2018, 495-496 (2010)
Lindsay M Webb et al.
The Journal of clinical investigation, 130(4), 1683-1698 (2020-02-25)
Protein arginine methyltransferase 5 (PRMT5) catalyzes symmetric dimethylation (SDM) of arginine, a posttranslational modification involved in oncogenesis and embryonic development. However, the role and mechanisms by which PRMT5 modulates Th cell polarization and autoimmune disease have not yet been elucidated.
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