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Merck
CN

700068P

Avanti

zymosterol

Avanti Research - A Croda Brand

Synonym(s):

110802

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About This Item

Empirical Formula (Hill Notation):
C27H44O
CAS Number:
Molecular Weight:
384.64
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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description

5α-cholesta-8,24-dien-3β-ol

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (700068P-1mg), pkg of 1 × 5 mg (700068P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand

shipped in

dry ice

storage temp.

−70°C

SMILES string

O[C@@H]1C[C@H]2[C@](CC1)(C3=C([C@H]4[C@@]([C@H](CC4)[C@@H](CCC=C(C)C)C)(CC3)C)CC2)C

InChI

1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h7,19-21,23-24,28H,6,8-17H2,1-5H3/t19-,20+,21+,23-,24+,26+,27-/m1/s1

InChI key

CGSJXLIKVBJVRY-XTGBIJOFSA-N

General description

Zymosterol acts as an intermediate in the biosynthesis of cholesterol from lanosterol.

Application


  • The ATPase activity of ABCA1 is increased by cholesterol in the presence of anionic lipids.: This study investigates the modulation of ATPase activity by cholesterol and anionic lipids, with a focus on the role of zymosterol in this biochemical pathway. The findings contribute to our understanding of lipid transport mechanisms and their implications in metabolic syndromes, emphasizing the potential therapeutic targets within these pathways (Sakata K et al., 2024).

  • Effects of continuous intravenous infusion with propofol on intestinal metabolites in rats.: This research utilizes zymosterol as a biomarker to study the effects of propofol on intestinal metabolites, providing insights into the metabolic impacts of anesthesia on lipid biosynthesis pathways. The results are crucial for optimizing anesthesia protocols and understanding their systemic effects (Li J et al., 2024).

Packaging

5 mL Amber Glass Screw Cap Vial (700068P-1mg)
5 mL Amber Glass Screw Cap Vial (700068P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

No data available

flash_point_c

No data available



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Sterol synthesis: a simple method for the isolation of zymosterol (5 alpha-cholesta-8, 24-dien-3 beta-ol) from yeast and spectral properties of zymosterol.
Taylor UF, et al.
Journal of Lipid Research, 22(1), 171-177 (1981)



Global Trade Item Number

SKUGTIN
700068P-1MG04061835384808
700068P-5MG04061835383481
700068P-10MG04061835384792