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710332C

Avanti

14:0 Cardiolipin (ammonium salt)

Name: 14:0 Cardiolipin (ammonium salt)
Brand: AVANTI

Avanti Research^™ - A Croda Brand

Synonym(s):

1,1′,2,2′-tetramyristoyl cardiolipin (ammonium salt); 1,1′,2,2′-tetratetradecanoyl cardiolipin (ammonium salt); CL(1′-[14:0/14:0],3′-[14:0/14:0])

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About This Item

Empirical Formula (Hill Notation):

C₆₅H₁₃₂N₂O₁₇P₂

CAS Number:

63988-20-5

Molecular Weight:

1275.69

MDL number:

MFCD28359035

NACRES:

NA.25

UNSPSC Code:

51191904

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Properties

Product Name

14:0 Cardiolipin (ammonium salt), 1′,3′-bis[1,2-dimyristoyl-sn-glycero-3-phospho]-glycerol (ammonium salt), chloroform

assay

>99% (TLC)

form

solution

packaging

pkg of 1 × 2.5 mL (710332C-25mg)

manufacturer/tradename

Avanti Research^™ - A Croda Brand 710332C

concentration

10 mg/mL (710332C-25mg)

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

Description

General description

14:0 Cardiolipin is an acidic phospholipid. Structurally, cardiolipin comprises three glycerol moieties and four acyl chains and is localized in the inner membrane of mitochondria. 14:0 Cardiolipin contains four myristic acid as acyl chain.

Application

14:0 Cardiolipin (1′,3′-bis[1,2-dimyristoyl-sn-glycero-3-phospho]-glycerol (ammonium salt)) has been used:

as a standard in tandem mass spectrometry
in the preparation of membrane proximal region (MPR) of human immunodeficiency virus (HIV-1) glycoprotein 41 (gp41)-lipopeptide conjugate and liposomes
as a component of micelle for suspending C8 ceramide substrate in ceramide kinase assay

Biochem/physiol Actions

Cardiolipin (CL) plays a key role in oxidative phosphorylation. CL is essential for energy production and in the activation of apoptosis. Deficiency of CL is associated with the development of diabetes and age-related heart failure. Anomalies associated with CL composition is observed in Barth Syndrome (BTHS).

Packaging

5 mL Clear Glass Sealed Ampule (710332C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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pictograms

GHS06,GHS08

signalword

Danger

hcodes

H302,H315,H319,H331,H336,H351,H361d,H372,H412

pcodes

P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk

WGK 3

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

flash_point_f

does not flash

flash_point_c