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Merck
CN

800741P

Avanti

N-18:1 L-Serine

Avanti Research™ - A Croda Brand

Synonym(s):

1-(9Z-octadecenoyl)-L-serine; (S)-3-hydroxy-2-(9Z)- octadecenamidopropanoate; (S)-3-hydroxy-2-oleoamidopropanoate

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About This Item

Empirical Formula (Hill Notation):
C21H39NO4
CAS Number:
1246302-99-7
Molecular Weight:
369.54
MDL number:
MFCD11878489
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

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Product Name

N-18:1 L-Serine, N-oleoyl L-serine, powder

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 5 mg (800741P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 800741P

lipid type

bioactive lipids
phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

General description

N-18:1 L-Serine is a N-acyl amino acid. The amino acid and the fatty acid acyl moiety are covalently linked by amide bond.

Biochem/physiol Actions

N-acyl amino acids are signaling molecules and N-acyl-serine is an endogenous orphan lipid mediator. N-oleoyl serine mediates energy homeostasis and bone metabolism. It also participates in the mitogenic signaling in osteoblasts and is a novel antiosteoporotic drugs.

Packaging

5 mL Amber Glass Screw Cap Vial (800741P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

No data available

Flash Point(C)

No data available

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Natalia Battista et al.
Biomolecules, 9(12) (2019-12-11)
The lipid signal is becoming increasingly crowded as increasingly fatty acid amide derivatives are being identified and considered relevant therapeutic targets. The identification of N-arachidonoyl-ethanolamine as endogenous ligand of cannabinoid type-1 and type-2 receptors as well as the development of
Reem Smoum et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(41), 17710-17715 (2010-09-30)
Bone mass is determined by a continuous remodeling process, whereby the mineralized matrix is being removed by osteoclasts and subsequently replaced with newly formed bone tissue produced by osteoblasts. Here we report the presence of endogenous amides of long-chain fatty

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