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810143P

Avanti

14:0 NBD PE

Avanti Polar Lipids 810143P, powder

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Synonym(s):
1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-(7-nitro-2-1,3-benzoxadiazol-4-yl) (ammonium salt)
Empirical Formula (Hill Notation):
C39H70N5O11P
CAS Number:
474942-82-0
Molecular Weight:
815.97
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (810143P-1mg)
pkg of 5 × 1 mg (810143P-5mg)

manufacturer/tradename

Avanti Polar Lipids 810143P

shipped in

dry ice

storage temp.

−20°C

General description

N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is a fluorescently labeled lipid localized at the membrane interface. Phosphoethanolamine is the second most abundant, metabolically related aminophospholipid. It is mostly enriched in brain.

Application

14:0 NBD PE may be used in the lipid mixing assay for the preparation of phospholipid vesicles and to study its non-equilibrium and equilibrium variations in thermodynamic state of the lipid-water-interface

Biochem/physiol Actions

Phosphoethanolamine of cardiac myocytes is known to prevent cellular damage after ischemia. N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) contributes to the Red edge excitation shift (REES) effect monitoring because of its unique motional and dielectric properties.

Packaging

5 mL Amber Glass Screw Cap Vial (810143P-1mg)
5 mL Amber Glass Screw Cap Vial (810143P-5mg)

Storage Class Code

11 - Combustible Solids

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Application of NBD-labeled lipids in membrane and cell biology
Fluorescent methods to study biological membranes, 37-50 (2012)
In vitro Membrane Interaction and Liposome Fusion Assays Using Recombinant Hepatitis C Virus Envelope Protein E2
Shrivastava S and Schneider MF
Bio-protocol, 8(23), 543-554 (2018)
Shamit Shrivastava et al.
PloS one, 8(7), e67524-e67524 (2013-07-19)
Fluorescent dyes are vital for studying static and dynamic patterns and pattern formation in cell biology. Emission properties of the dyes incorporated in a biological interface are known to be sensitive to their local environment. We report that the fluorescence
Jean E Vance et al.
Biochimica et biophysica acta, 1831(3), 543-554 (2012-09-11)
Phosphatidylserine (PS) and phosphatidylethanolamine (PE) are metabolically related membrane aminophospholipids. In mammalian cells, PS is required for targeting and function of several intracellular signaling proteins. Moreover, PS is asymmetrically distributed in the plasma membrane. Although PS is highly enriched in

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