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About This Item
Empirical Formula (Hill Notation):
C33H56N5O11P
CAS Number:
Molecular Weight:
729.80
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
Product Name
16:0-06:0 NBD PE, Avanti Research™ - A Croda Brand 810153C
Assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (810153C-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810153C
concentration
1 mg/mL (810153C-1mg)
shipped in
dry ice
storage temp.
−20°C
General description
N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is a fluorescent probe which contains NBD attached to the headgroup of phosphatidylethanolamine and localized at the membrane interface. Phosphoethanolamine is the second most abundant, metabolically related aminophospholipid. It is mostly enriched in brain.
Application
16:0-06:0 NBD PE is suitable for the determination of enzyme substrate specificity of lipoteichoic acid synthase (LtaS).
Biochem/physiol Actions
Phosphoethanolamine (PE) acts as a substrate for several phospholipids of the cell membrane. N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) aids in monitoring the Red edge excitation shift (REES) effects with its unique motional and dielectric properties.
Packaging
5 mL Amber Glass Screw Cap Vial (810153C-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
Target Organs
Central nervous system, Liver,Kidney
WGK
WGK 3
Regulatory Information
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Application of NBD-labeled lipids in membrane and cell biology
Fluorescent methods to study biological membranes, 37-50 (2012)
Maria Mercedes Palomino et al.
Microbiology (Reading, England), 159(Pt 11), 2416-2426 (2013-09-10)
The probiotic Gram-positive bacterium Lactobacillus casei BL23 is naturally confronted with salt-stress habitats. It has been previously reported that growth in high-salt medium, containing 0.8 M NaCl, leads to modifications in the cell envelope of this bacterium. In this study
Adilson Kleber Ferreira et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 67(6), 481-487 (2013-06-19)
Phosphoethanolamine (Pho-s) is a compound involved in phospholipid turnover, acting as a substrate for many phospholipids of the cell membranes. In a recent study, we showed that Pho-s has antitumor effect in the several tumor cells. In this study we
Mirka E Wörmann et al.
Molecular microbiology, 79(3), 566-583 (2011-01-25)
Lipoteichoic acid (LTA) is an important cell wall polymer in Gram-positive bacteria. The enzyme responsible for polyglycerolphosphate LTA synthesis is LtaS, first described in Staphylococcus aureus. Four LtaS orthologues, LtaS(BS) , YfnI, YqgS and YvgJ, are present in Bacillus subtilis.
Jean E Vance et al.
Biochimica et biophysica acta, 1831(3), 543-554 (2012-09-11)
Phosphatidylserine (PS) and phosphatidylethanolamine (PE) are metabolically related membrane aminophospholipids. In mammalian cells, PS is required for targeting and function of several intracellular signaling proteins. Moreover, PS is asymmetrically distributed in the plasma membrane. Although PS is highly enriched in
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