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About This Item
Empirical Formula (Hill Notation):
C41H70N5O11P
CAS Number:
Molecular Weight:
840.00
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
Product Name
18:1-12:0 NBD PE, Avanti Research™ - A Croda Brand 810156C
Assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (810156C-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810156C
concentration
1 mg/mL (810156C-1mg)
shipped in
dry ice
storage temp.
−20°C
General description
N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is localized at the membrane interface. Fluorescent NBD label is covalently linked to the headgroup of phosphatidylethanolamine. Phosphoethanolamine is mostly present in brain and is the second most abundant, metabolically related aminophospholipid.
Application
18:1-06:0 NBD PE may be used as a component of liposome in cross-linking experiment and to determine M13 coat protein selectivity toward phospholipids headgroups.
Biochem/physiol Actions
N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) plays a key role as a fluorescent analog in the studies of organization and dynamics of membranes. NBD PE contributes in monitoring Red edge excitation shift (REES) effects with the unique motional and dielectric properties it possesses.
Packaging
5 mL Amber Glass Screw Cap Vial (810156C-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
Target Organs
Central nervous system, Liver,Kidney
WGK
WGK 3
Regulatory Information
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Synthetic phosphoethanolamine induces cell cycle arrest and apoptosis in human breast cancer MCF-7 cells through the mitochondrial pathway
Ferreira AK, et al.
Biomedicine / [Publiee Pour L'A.A.I.C.I.G.], 67(6), 481-487 (2013)
The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy
Hanada T, et al.
Journal of biological and chemical chronicles, 282(52), 37298-37302 (2007)
Fluorescent methods to study biological membranes, 37-50 (2012)
Cardiolipin and phosphatidylethanolamine role in dibucaine interaction with the mitochondrial membrane
Lopes SC, et al.
Biochimica et Biophysica Acta, 1861(6), 1152-1161 (2019)
The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy
Fernandes F, et al.
Biophysical Journal, 282(52), 37298-37302 (2007)
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