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About This Item
Empirical Formula (Hill Notation):
C42H73N6O13P
CAS Number:
Molecular Weight:
901.04
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
Product Name
18:1-12:0 NBD PS, Avanti Research™ - A Croda Brand 810195C
Assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mL (810195C-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810195C
concentration
1 mg/mL (810195C-1mg)
shipped in
dry ice
storage temp.
−20°C
General description
Phosphatidylserine (PS) is a minor membrane phospholipid. This anionic phospholipid contains a polar head group and two long hydrophobic acyl chains. 1 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) PS is a fluorescent probe containing NBD at the headgroup of PS.
Application
18:1-12:0 NBD PS or 1-oleoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphoserine (ammonium salt) has been used in donor liposomes to determine the phospholipid transfer activity of the synaptic vesicle membrane protein, VAT-1 and phosphatidic acid (PA) transfer by Ups1−Mdm35 system in mitochondria. 18:1-12:0 NBD PS is also suitable for the determination of in vitro phosphatidylserine decarboxylase (Psd1) activity.
Packaging
5 mL Amber Glass Screw Cap Vial (810195C-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
Target Organs
Central nervous system, Liver,Kidney
WGK
WGK 3
Regulatory Information
易制毒化学品（2类）
危险化学品
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Structural and mechanistic insights into phospholipid transfer by Ups1?Mdm35 in mitochondria
Yasunori W, et al.
Nature Communications null
The distribution and function of phosphatidylserine in cellular membranes
Leventis PA and Grinstein S
Annual Review of Biophysics null
Phosphatidylserine and the human brain
Glade MJ and Smith K
Nutrition null
Structural Basis for Phosphatidylethanolamine Biosynthesis by Bacterial Phosphatidylserine Decarboxylase
Yasunori W, et al.
Structure null
Lipid Homeostasis Is Maintained by Dual Targeting of the Mitochondrial PE Biosynthesis Enzyme to the ER
Jonathan R, et al.
Developmental Cell null
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