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810211C

Avanti

C12-NBD Ceramide

Name: C12-NBD Ceramide
Brand: AVANTI

Avanti Research^™ - A Croda Brand

别名:

N-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-D-erythro-sphingosine

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关于此项目

经验公式（希尔记法）:

C₃₆H₆₁N₅O₆

化学文摘社编号:

202850-01-9

分子量:

659.90

MDL number:

MFCD02259239

UNSPSC Code:

12352211

NACRES:

NA.25

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属性

产品名称

C12-NBD Ceramide, Avanti Research^™ - A Croda Brand 810211C

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810211C-1mg)

manufacturer/tradename

Avanti Research^™ - A Croda Brand 810211C

concentration

1 mg/mL (810211C-1mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[N+](=O)([O-])c1c2n[o]nc2c(cc1)NCCCCCCCCCCCC(=O)N[C@H]([C@H](O)\C=C\CCCCCCCCCCCCC)CO

InChI

1S/C36H61N5O6/c1-2-3-4-5-6-7-8-9-10-12-15-18-21-24-33(43)31(29-42)38-34(44)25-22-19-16-13-11-14-17-20-23-28-37-30-26-27-32(41(45)46)36-35(30)39-47-40-36/h21,24,26-27,31,33,37,42-43H,2-20,22-23,25,28-29H2,1H3,(H,38,44)/b24-21+/t31-,33+/m0/s1

InChI key

SNOJCYCOPNIGIK-ULETYAGTSA-N

说明

Application

C12-NBD ceramide is suitable for its use:

as a substrate to measure the activity of acid, alkaline and neutral ceramidases
in in vitro ceramidase activity assay
in ceramide phosphoethanolamine (CPE) synthase assay to determine the K_m and V_max of sphingomyelin synthase (SMS1, SMS2, and SMSr)

Biochem/physiol Actions

Ceramide is one of the products of sphingolipid metabolism. The members of ceramide synthase family are responsible for its synthesis. Each ceramide synthesized differs in its acyl chain length. Ceramides possess a wide range of functions, associated with apoptosis, cancer inhibition and chemotherapy. Its action is also related to neurodegenerative diseases.

Packaging

5 mL Amber Glass Screw Cap Vial (810211C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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pictograms

GHS06,GHS08

signalword

Danger

hcodes

H302,H315,H319,H331,H336,H351,H361d,H372

pcodes

P201 - P260 - P264 - P280 - P304 + P340 + P311 - P403 + P233

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

wgk

WGK 3

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

flash_point_f

does not flash

flash_point_c