跳转至内容
Merck
CN

810211C

Avanti

C12-NBD Ceramide

Avanti Research™ - A Croda Brand

别名:

N-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-D-erythro-sphingosine

登录 查看组织和合同定价。

选择尺寸

关于此项目

经验公式（希尔记法）:
C36H61N5O6
化学文摘社编号:
202850-01-9
分子量:
659.90
MDL number:
MFCD02259239
UNSPSC Code:
12352211
NACRES:
NA.25

主要文件

查看所有文档
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

产品名称

C12-NBD Ceramide, Avanti Research™ - A Croda Brand 810211C

SMILES string

[N+](=O)([O-])c1c2n[o]nc2c(cc1)NCCCCCCCCCCCC(=O)N[C@H]([C@H](O)\C=C\CCCCCCCCCCCCC)CO

InChI

1S/C36H61N5O6/c1-2-3-4-5-6-7-8-9-10-12-15-18-21-24-33(43)31(29-42)38-34(44)25-22-19-16-13-11-14-17-20-23-28-37-30-26-27-32(41(45)46)36-35(30)39-47-40-36/h21,24,26-27,31,33,37,42-43H,2-20,22-23,25,28-29H2,1H3,(H,38,44)/b24-21+/t31-,33+/m0/s1

InChI key

SNOJCYCOPNIGIK-ULETYAGTSA-N

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810211C-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 810211C

concentration

1 mg/mL (810211C-1mg)

shipped in

dry ice

storage temp.

−20°C

正在寻找类似产品? 访问 产品对比指南

Application

C12-NBD ceramide is suitable for its use:
  • as a substrate to measure the activity of acid, alkaline and neutral ceramidases
  • in in vitro ceramidase activity assay
  • in ceramide phosphoethanolamine (CPE) synthase assay to determine the Km and Vmax of sphingomyelin synthase (SMS1, SMS2, and SMSr)

Biochem/physiol Actions

Ceramide is one of the products of sphingolipid metabolism. The members of ceramide synthase family are responsible for its synthesis. Each ceramide synthesized differs in its acyl chain length. Ceramides possess a wide range of functions, associated with apoptosis, cancer inhibition and chemotherapy. Its action is also related to neurodegenerative diseases.

Packaging

5 mL Amber Glass Screw Cap Vial (810211C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

wgk

WGK 3

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

flash_point_f

does not flash

flash_point_c

does not flash

法规信息

新产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our 文件 section.

如需帮助，请联系 客户支持

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

A Critical Role for Ceramide Synthase 2 in Liver Homeostasis I. ALTERATIONS IN LIPID METABOLIC PATHWAYS
Pewzner JY, et al.
The Journal of Biological Chemistry, 285(14), 10902-10910 (2010)
The ATP-binding cassette transporter-2 (ABCA2) overexpression modulates sphingosine levels and transcription of the amyloid precursor protein (APP) gene
Davis W
Current Alzheimer Research, 12(9), 847-859 (2015)
All members in the sphingomyelin synthase gene family have ceramide phosphoethanolamine synthase activity
Ding T, et al.
Journal of Lipid Research, 56(3), 537-545 (2015)
Mammalian ceramide synthases
Levy M and Futerman AH
IUBMB Life, 62(5), 347-356 (2010)
Li-Yu Chen et al.
Nature communications, 6, 6030-6030 (2015-01-17)
Turgor pressure plays pivotal roles in the growth and movement of walled cells that make up plants and fungi. However, the molecular mechanisms regulating turgor pressure and the coordination between turgor pressure and cell wall remodelling for cell growth remain

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持